Nanoparticle-based intervention to cardiovascular diseases (CVDS)

Abstract

Cardiovascular diseases are the major cause of death universally and are major contributors to health-care cost. Enormous progress has been made to detect cardiovascular diseases but there is an immediate need for developing of rapid and early detection of cardiovascular diseases as the conventional diagnostic approach focuses on the molecular imaging and detection of CVD-associated biomarkers. To attenuate the progression of cardiovascular diseases rapid and accurate diagnostic techniques are required. Nanomaterials provides a potential platform for the development of diagnostic tools because of their promising physiochemical properties. NPs such as gold nanoparticles, quantum dots, lipids, polymeric nanoparticles can be a valuable source to target cardiovascular diseases. The successful application of nanomaterials for cardiovascular diseases needs a detailed understanding of both the disease and targeting moieties. In this review we discuss about various nano-biosensors for the detection of cardiac biomarkers, the enhancement of imaging techniques using molecular imaging and nanoparticle mediated drug delivery for cardiovascular diseases.