MULTIPLE INFLAMMATORY SYNDROME IN CHILDREN (MIS-C) ASSOCIATED WITH COVID-19

Tinatin Kutubidze, Maia Kherkheulidze, M. Kobakhidze, Irine Kekelidze, E. Nakhutsrishvili
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Abstract

There is a difference between MIS-C and KD. This is probably a postinfectious inflammatory response manifested with elevation of inflammatory markers and signs of myocardial damage. So, MIS-C could be an analogue of late phase COVID-19, which we are seeing in adult patients. This phase is also characterized by “cytokine storm” and can include severe myocardial disfunction, renal damage and laboratory changes consistent with MAS. Despite growing numbers of children with MIS-C, it still remains as rare condition and has good outcome in majority of cases. Children with MIS-C need special care of rheumatologist, infectious disease and intensive disease specialist collaboration.
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与COVID-19相关的儿童多发性炎症综合征(misc
misc和KD之间存在差异。这可能是一种感染后炎症反应,表现为炎症标志物升高和心肌损伤的迹象。因此,MIS-C可能是我们在成年患者中看到的晚期COVID-19的类似物。这一阶段还以“细胞因子风暴”为特征,可包括严重的心肌功能障碍、肾损害和与MAS一致的实验室改变。尽管越来越多的儿童患有MIS-C,但它仍然是一种罕见的疾病,大多数情况下预后良好。患有misc的儿童需要风湿病专家、传染病专家和疾病专家的密切合作的特殊照顾。
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