Role of Biotransformation Based on Intestinal Flora in the Research and Development of TCM

Xin Liu
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Abstract

Introduction Traditional Chinese Medicine (TCM) is of great significance to the research and development of new drugs due to its various active components. Meanwhile, as the focus of current research, biotransformation greatly stimulates the investigation of TCM. Intestine is the primary place for the metabolism of oral drugs in the human body, where a number of parasite bacteria flora play an inevitable role in the biotransformation of drugs. Thus, it is obviously that the biotransformation based on intestinal flora is a powerful tool in the development of TCM.
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基于肠道菌群的生物转化在中药研发中的作用
中药具有多种有效成分,对新药的研究和开发具有重要意义。同时,生物转化作为当前的研究热点,极大地刺激了中医的研究。肠道是人体口服药物代谢的主要场所,许多寄生菌群在肠道中对药物的生物转化起着不可避免的作用。可见,以肠道菌群为基础的生物转化是中医药发展的有力工具。
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