{"title":"Run Probability of High-Order Seed Patterns and its Applications to Finding Good Transition Seeds","authors":"Jialiang Yang, Louxin Zhang","doi":"10.1142/9781848161092_0015","DOIUrl":null,"url":null,"abstract":"Transition seeds exhibit a good tradeofi between sensitivity and speciflcity for homology search in both coding and non-coding regions. But, identifying good transition seeds is extremely hard. We study the hit probability of high-order seed patterns. Based on our theoretical results, we propose an e‐cient method for ranking transition seeds for seed design.","PeriodicalId":74513,"journal":{"name":"Proceedings of the ... Asia-Pacific bioinformatics conference","volume":"57 1","pages":"123-132"},"PeriodicalIF":0.0000,"publicationDate":"2007-12-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the ... Asia-Pacific bioinformatics conference","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1142/9781848161092_0015","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
Transition seeds exhibit a good tradeofi between sensitivity and speciflcity for homology search in both coding and non-coding regions. But, identifying good transition seeds is extremely hard. We study the hit probability of high-order seed patterns. Based on our theoretical results, we propose an e‐cient method for ranking transition seeds for seed design.
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