Positive Result for SARS-CoV-2 RNA Test after a Long Time for the Patient with COVID-19 even after Discharge from the Hospital

M. Fazeli, Saman Pazira, Behzad Pourhossein, A. Rasooli, N. Ansari, F. Jalilian
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Abstract

Background: Ruthin's coronavirus disease 2019 (COVID-19) diagnosis is based on the positive result of real-time polymerase chain reaction (PCR) from the nasal and oropharyngeal swab. However, chest CT scans can play an important role in diagnosing patients with COVID-19. Cases Report: In this study, we reported a 44 years old female with a mild form of the COVID-19 who showed a positive result for the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA for 44 days after symptom onset. The suspected case was detected using real-time PCR. After two weeks of hospitalization, the patient was discharged, but her molecular tests were performed twice after one month and 44 days, and they remained positive for SARS-CoV-2 RNA. Conclusion: In theory, if the patient becomes re-infected or the virus reacts, these individuals may serve as a transmission source. So far, the only way to screen for possible reinfection has been by using PCR on separate specimens.
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COVID-19患者出院后长时间SARS-CoV-2 RNA检测呈阳性
背景:Ruthin's冠状病毒病2019 (COVID-19)的诊断基于鼻口咽拭子实时聚合酶链反应(PCR)阳性结果。然而,胸部CT扫描可以在诊断COVID-19患者方面发挥重要作用。病例报告:在本研究中,我们报告了一名患有轻度COVID-19的44岁女性,在症状出现44天后,她的严重急性呼吸综合征冠状病毒2 (SARS-CoV-2) RNA检测结果呈阳性。实时荧光定量PCR检测疑似病例。住院两周后,患者出院,但在1个月零44天后,她进行了两次分子检测,结果仍为SARS-CoV-2 RNA阳性。结论:理论上,如果患者再次感染或病毒发生反应,这些个体可能成为传播源。到目前为止,筛选可能的再感染的唯一方法是对单独的标本使用PCR。
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