An Ultrasound Mediated Green Synthesis of Benzimidazolylthiounsaturatednitriles Using Water as a Green Solvent

S. Rao, C. V. Reddy, P. Dubey
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引用次数: 3

Abstract

Reaction of 2-cyanothiomethylbenzimidazole  1 with an aromatic aldehydes in water under ultrasonic irradiation for 10–13 min gave the corresponding unsaturated nitriles 2a–h which is an efficient and simple method under green conditions. The unsaturated nitrile derivatives were obtained in 86–98% yield with a short reaction time without any tedious workup procedures.
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超声介导的以水为绿色溶剂的苯并咪唑基硫不饱和腈的绿色合成
2-氰硫甲基苯并咪唑1与芳香族醛在水中在超声波照射下反应10-13 min,得到相应的不饱和腈2a-h,这是绿色条件下一种高效、简便的方法。不饱和腈衍生物的收率为86-98%,反应时间短,无需繁琐的后处理程序。
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