Effects Of Pyeloplasty in Infants with Failing Kidneys Over the Long Term

Arshad Jamal, R. Singh
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Abstract

Objective: The most typical type of obstruction in the upper urinary tract is ureteropelvic junction obstruction or UPJO. The objective of this study was to assess the effectiveness and long-term results of pyeloplasty in children with poorly functioning kidneys. Method: Patients who underwent pyeloplasty at Department of Urology, Rajendra Institute of Medical Science, Ranchi for last twelve years were the subject of a retrospective data study. Postoperative outcome was the parameter under study. Success was measured by either symptom improvement or better drainage on postoperative Tc-99m DTPA renography, which was performed after two months and then yearly after that. Results: 60 individuals were enrolled in the study, with a mean age of 8.5 years (3 months to 12 years), a male-to-female ratio of 2:1, and poor function on the isotope renogram (31%). The ratio of left to right sides was 1.2:1. All patients had dismembered pyeloplasty procedures. 37 patients (66.8%) underwent laparoscopic pyeloplasty, whereas 23 (33.2%) underwent open surgery. 35 patients had follow-up renograms available; of these, 30 showed improved drainage and no further decline in renal function, while 5 displayed an obstructed pattern; of these, 3 patients had noticeably worsened split function, and the other two underwent a second open pyeloplasty. A mean follow-up of 21.5 months revealed a 91% overall success rate. Conclusion: In the pediatric age group, pyeloplasty provides satisfactory intermediate results in kidneys with inadequate function.
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肾盂成形术对长期肾功能衰竭婴儿的影响
目的:上尿路梗阻最典型的类型是肾盂输尿管交界处梗阻或UPJO。本研究的目的是评估肾盂成形术对肾功能不佳儿童的有效性和长期结果。方法:对近12年来在Ranchi Rajendra医学研究所泌尿外科行肾盂成形术的患者进行回顾性研究。术后预后为研究参数。通过术后Tc-99m DTPA肾造影术的症状改善或引流改善来衡量是否成功,术后2个月进行Tc-99m DTPA肾造影术,此后每年进行一次。结果:60人被纳入研究,平均年龄为8.5岁(3个月至12岁),男女比例为2:1,同位素肾图功能差(31%)。左右两边的比例为1.2:1。所有患者均行肢解肾盂成形术。37例(66.8%)行腹腔镜肾盂成形术,23例(33.2%)行开放手术。35例患者有随访心电图;其中30例引流改善,肾功能无进一步下降,5例出现梗阻;其中,3例患者分裂功能明显恶化,另外2例接受了第二次开放肾盂成形术。平均随访21.5个月,总成功率为91%。结论:在儿童年龄组,肾盂成形术对肾功能不全的肾脏提供了满意的中间结果。
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