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A Rare Case of Placental Site Trophoblastic Tumor 罕见的胎盘部位滋养细胞瘤1例
Pub Date : 2023-06-15 DOI: 10.59657/2837-8172.brs.23.025
Y. Wijeratne, Chintana Hapuachchige, Madara Ojithmali, Namal Wickramasinghe, Sanjaya Nagasinghe
Placental site trophoblastic tumor (PSTT) is a rare entity of malignant gestational trophoblastic neoplasia (GTN) with an incidence of 0.23 to 3% of all gestational trophoblastic diseases (GTD). They originate from intermediate trophoblastic cells of the placenta. They are slow-growing tumors and less chemo sensitive. Per vaginal bleeding following a miscarriage is not uncommon, however malignant variants of gestational trophoblastic neoplasia also could be a possibility. We are reporting a 24-year-old who was an otherwise healthy female who presented with persistent per vaginal bleeding following the first-trimester miscarriage in her second pregnancy. Initial histology of suction evacuation for her miscarriage has shown a partial mole. Since she continues to have per vaginal bleeding even a month later, repeat evacuation was done and beta hCG was high (2132mIU/ml), she was treated with a methotrexate regime. During follow up there was a slow rising of beta hCG level and hysterectomy was carried out due to the suspicions of invasive mole or PSTT. Histology confirmed a placental site trophoblastic tumor and her recovery and follow-up were uneventful.
胎盘部位滋养细胞瘤(PSTT)是一种罕见的妊娠期恶性滋养细胞瘤(GTN),发病率为妊娠期滋养细胞疾病(GTD)的0.23 ~ 3%。它们起源于胎盘的中间滋养细胞。它们是生长缓慢的肿瘤,对化疗不太敏感。流产后阴道出血并不罕见,但妊娠滋养细胞瘤的恶性变异也可能发生。我们报告了一位24岁的健康女性,她在第二次怀孕的早期流产后出现持续的阴道出血。她流产的初步吸出组织学显示局部痣。由于她在一个月后仍有阴道出血,重复抽液,hCG高(2132mIU/ml),她接受甲氨蝶呤治疗。随访期间β - hCG水平缓慢上升,因怀疑有侵袭性痣或PSTT而行子宫切除术。组织学证实为胎盘部位滋养细胞瘤,恢复和随访顺利。
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引用次数: 1
Post-Traumatic Feelings of Vulnerability, Psychological Disability, And Connection to Others in Victims of the 2016 Seka Train Derailment in Cameroon 2016年喀麦隆塞卡火车脱轨事件受害者的创伤后脆弱感、心理残疾以及与他人的联系
Pub Date : 2023-06-15 DOI: 10.59657/2837-8172.brs.23.021
Goula Tojuin Boris, Ngeh David Nkarnyu
The problem here is that of the restructuring of the link to the other of the psych traumatized person. The objective here is to apprehend the mechanism by which the feeling of vulnerability in the victim of a serious traffic accident, entered in a situation of disability, affects his or her link to the other. Following a qualitative approach, focused on the case study, the data were collected through semi-directive interviews with three victims of the 2016 Seka train accident. For this purpose, thematic content analysis was favoured. According to the results, the link to the other of the psych traumatized person (PP) is declined according to the instinctual unbinding, the attempt of the ego to restore the balance within the psychic spaces in humans. Also, they show that after a serious traffic accident, the organizers of the link are re-focused and can preserve their initial character just as they can be tainted by a feeling of pity. In this case, they plunge the victim into a fusional and/or conflictual relationship, generating a feeling of uselessness, a functional discomfort and a decrease or even a loss of self-esteem.
这里的问题是精神创伤患者与他人之间的联系的重建。这里的目标是了解严重交通事故受害者在残疾情况下的易受伤害感如何影响他或她与他人的联系的机制。采用定性方法,以案例研究为重点,通过对2016年Seka火车事故的三名受害者进行半指令性访谈来收集数据。为此目的,建议进行专题内容分析。根据结果,心理创伤者(PP)与他人的联系是根据本能的解除束缚而被拒绝的,这是自我在人类心理空间内恢复平衡的尝试。此外,他们还展示了在一次严重的交通事故之后,链接的组织者重新聚焦,可以保持他们最初的性格,就像他们可以被怜悯的感觉所玷污一样。在这种情况下,他们使受害者陷入一种融合和/或冲突的关系中,产生一种无用的感觉,一种功能上的不适,自尊的减少甚至丧失。
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引用次数: 0
Multiple Polycystic Organs in A Middle Age Female: A Rare Case of More Than Ten Years Without Surgical Intervention 一例中年女性多发性多囊器官:罕见病例超过十年未手术治疗
Pub Date : 2023-06-15 DOI: 10.59657/2837-8172.brs.23.027
Randa Zaki A M Khair, Mohamed Toum Musa M Ibrahim
Some organs are recognized to develop cysts more common than others do; these include the kidney the liver, the pancreas and the spleen. The structure and function of these organs may play a role. The frequency of polycystic kidney is variable. It is reported as 50 or less in 100000 (5 in 10000), 1 in 400 and 1 in 1000 life birth. Prevalence of autosomal dominant polycystic kidney disease (ADPKD) is thought to be overestimated by 2 to 5 folds. Multiple polycystic organs are not common, and reviewing the literature revealed some case reports, which indicates that such cases do not have regular pattern. Inherited polycystic kidney disease has two varieties; autosomal dominant polycystic kidney disease (ADPKD) and autosomal recessive polycystic kidney disease (ARPKD).
有些器官被认为比其他器官更容易出现囊肿;这些器官包括肾脏、肝脏、胰腺和脾脏。这些器官的结构和功能可能起作用。多囊肾的发生频率是可变的。据报道,10万人中有50人或更少(10000人中有5人),400人中有1人,1000人中有1人出生。常染色体显性多囊肾病(ADPKD)的患病率被认为被高估了2至5倍。多发性多囊器官并不常见,回顾文献发现一些病例报道,表明此类病例无规律性。遗传性多囊肾病有两个品种;常染色体显性多囊肾病(ADPKD)和常染色体隐性多囊肾病(ARPKD)。
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引用次数: 0
Medicinal Common Seed-Acorus Calamus 药用普通种子-菖蒲
Pub Date : 2023-06-15 DOI: 10.59657/2837-8172.brs.23.016
D.X. Tulayeva, L. T. Zakhidova, V.F. Tukhtasheva
This article covers the structure, distribution, chemical composition, and use of the common sedum plant in folk medicine and traditional medicine. It highlights the relevance of using this plant in the field of medicine. Acorus calamus is a perennial plant belonging to the Aceraceae family and is found in many countries. It contains various substances, including vitamin C. The plant is highly regarded in Indian traditional medicine and is known for rejuvenating the brain and nervous system. The rhizomes of Acorus calamus are widely used in the treatment of many diseases such as epilepsy, mental disorders, fever, abdominal pain, chronic diarrhea, liver, and kidney diseases.
本文介绍了景天属植物的结构、分布、化学成分及其在民间医学和传统医学中的应用。它突出了在医学领域使用这种植物的相关性。菖蒲是槭树科的多年生植物,在许多国家都有发现。它含有多种物质,包括维生素c。这种植物在印度传统医学中受到高度重视,以恢复大脑和神经系统的活力而闻名。菖蒲的根茎被广泛用于治疗许多疾病,如癫痫、精神障碍、发烧、腹痛、慢性腹泻、肝脏和肾脏疾病。
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引用次数: 0
A Vaccine for HIV HIV疫苗
Pub Date : 2023-06-15 DOI: 10.59657/2837-8172.brs.23.017
Alan Kleinman
HIV has been infecting people for more than 30 years. The viral genetic sequence is well known including viral proteins produced. Why haven't any successful vaccines for this infection been produced despite all this time passing and all this understanding of the virus? This paper presents the problems associated with the production of a useful vaccine, not just for HIV but for many other diseases as well.
30多年来,艾滋病毒一直在感染人类。病毒的基因序列是众所周知的,包括产生的病毒蛋白。为什么这么久过去了,人们对这种病毒有了这么多的了解,但还没有研制出有效的疫苗呢?这篇论文提出了与生产一种有用的疫苗有关的问题,这种疫苗不仅适用于艾滋病毒,也适用于许多其他疾病。
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引用次数: 0
The Aesthetic Restoration of Missing Anterior Teeth with A Dmls Prosthesis-A Case Report 用Dmls假体美学修复缺失前牙1例
Pub Date : 2023-04-01 DOI: 10.59657/2837-8172.brs.23.020
Nikhil Vitthal Dayama, M. Ali, P. Katiyar, Neeranshi Swaroop, Asra Z Ahmed, Mirza Hamza Baig
The most significant social connecting gesture and vital to professional advancement is a confident, appealing smile. Patients may experience social and psychological discomfort as a result of the loss of their anterior teeth. The contemporary dental situation provides numerous treatment options for the aesthetic and functional replacement of a congenitally or traumatically lost anterior tooth in young and adult patients, including implant crown, conventional FDP, Resin Bonded FDP, or RPD. The most important aspect of an aesthetic anterior restoration is patient satisfaction with the cosmetic and functional outcome of therapy. This case report discusses the aesthetic correction of missing maxillary and mandibular anterior teeth using intra-oral scanning and DMLS PFM crowns.
最重要的社交联系姿态和职业发展至关重要的是一个自信的,吸引人的微笑。由于前牙的脱落,患者可能会经历社会和心理上的不适。当代牙科的情况为年轻和成年患者先天性或外伤性前牙丢失提供了许多美观和功能替代的治疗选择,包括种植冠,传统FDP,树脂结合FDP或RPD。美学前牙修复最重要的方面是患者对治疗的外观和功能结果的满意度。本病例报告讨论了使用口腔内扫描和DMLS PFM冠对缺失的上颌和下颌前牙进行美学矫正。
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引用次数: 0
Chagas Disease in Children-Case Report 儿童恰加斯病病例报告
Pub Date : 2023-04-01 DOI: 10.59657/2837-8172.brs.23.015
Alicia Santa Cortes Gonzalez, V. García Torres, Maria Patricia Ramos Gonzalez, Rodolfo Ramirez Robles, Mariana Guerra Estevez, Diana Cristina Mancisidor Carreras, Alberto Hernandez Mota
Chagas disease, caused by Trypanosoma cruzi, is considered the most serious parasitosis in America. It is mainly transmitted by triatomics (bugs). The infection causes cardiomyopathies and mega organs of the digestive tract. The diagnosis in the acute phase is by parasitological approach and in the chronic phase, by laboratory screening studies. In Mexico, children under 10 years of age are the most affected. The case of a 12-year-old girl with data suggestive of a bacterial infectious process is reported. with persistent fever, multi-treated with antimicrobials with suspicion of Chagas disease through the route of entry of the parasite with the Romana-Mazza sign.
恰加斯病是由克氏锥虫引起的,被认为是美国最严重的寄生虫病。它主要是由三原子(虫子)传播的。这种感染会引起心肌病和消化道器官肿大。急性期的诊断是通过寄生虫学方法,慢性期的诊断是通过实验室筛查研究。在墨西哥,10岁以下的儿童受影响最大。病例12岁女孩的数据提示细菌感染过程报告。持续发热,多次接受抗微生物药物治疗,疑似恰加斯病,通过带有罗马-马扎标志的寄生虫进入途径。
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引用次数: 0
Study of Normal and Pathogenic Bacteria in Medicinal Probiotics 药用益生菌中正常菌和致病菌的研究
Pub Date : 2023-04-01 DOI: 10.59657/2837-8172.brs.23.013
T. Das, S. Bhattacharyya, S. Datta
There are many medicinal probiotics available which are usually bacteria but sometimes also yeasts. These medicinal probiotics, sometimes contain some undesired products like pathogenic aerobic or anaerobic bacteria. These are hitherto unexplored areas of public health research. Hence here we have tried to study the presence of these types of pathogenic bacteria. Some pathogens were found in the medicinal probiotics.
有许多可用的药用益生菌,通常是细菌,但有时也酵母。这些药用益生菌有时含有一些不需要的产物,如致病的好氧或厌氧细菌。这些是迄今为止公共卫生研究尚未探索的领域。因此,我们在这里试图研究这些类型的致病菌的存在。在药用益生菌中发现了一些致病菌。
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引用次数: 0
Entrance of Transverse Colon Volvulus into the Diaphragm Defect: A Case Report 横结肠扭转进入横膈膜缺损1例
Pub Date : 2023-04-01 DOI: 10.59657/2837-8172.brs.23.011
Navid Rahimi Zarei, Mohammad Hossein Golezar
Background: Colonic volvulus is an uncommon yet clinically important condition. It can occur in different locations; however, transverse colon and splenic flexure are rarely involved. We hereby present a 62-year-old man with a rare condition of herniation of transverse colon and splenic flexure within the chest cavity. Case presentation: A 62-year-old man was admitted to our center, a teaching hospital in Iran, complaining about three-day abdominal pain, anorexia, constipation, and abdominal distention. He was intellectually disabled and had a previous history of chronic constipation. The imaging studies showed the bowel loops herniated into the thoracic cavity. A laparotomy procedure was performed. The twisted transverse colon and splenic flexure were present in the left hemithorax. Total colectomy and ileostomy were performed and the diaphragmatic defect was repaired. Conclusion: This work aimed to raise attention to the rare condition of concurrent diaphragmatic hernia and colonic volvulus. The diaphragmatic hernia can be a life-threatening condition per se. If it is accompanied by intestinal volvulus in rare cases, it creates a pressing condition. More studies are required to explain the etiology of this potentially fatal condition.
背景:结肠扭转是一种罕见但临床上重要的疾病。它可以发生在不同的地方;然而,很少累及横结肠和脾屈曲。我们在此报告一位62岁的男性,患有罕见的横结肠疝和胸腔内脾脏屈曲。病例介绍:一名62岁男性患者入住我中心,伊朗一家教学医院,主诉腹痛三天,厌食,便秘,腹胀。他有智力障碍,以前有慢性便秘史。影像学检查显示肠袢疝入胸腔。进行剖腹手术。左半胸可见横结肠扭曲及脾弯曲。行全结肠切除术及回肠造口术,并修复膈缺损。结论:本文旨在引起人们对膈疝并发结肠扭转的重视。膈疝本身就是一种危及生命的疾病。如果在极少数情况下伴有肠扭转,则会造成急症。需要更多的研究来解释这种潜在致命疾病的病因。
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引用次数: 0
A Prospective Cohort Study of Psoriatic Arthritis Prevalence in a Serbian Patients with Psoriasis 塞尔维亚银屑病患者银屑病关节炎患病率的前瞻性队列研究
Pub Date : 2023-04-01 DOI: 10.59657/2837-8172.brs.23.010
E. Mahmutovic, Emir Bisevac, Ardea Milidrag, Z. Bajin, K. Boskovic, Z. Dolicanin
Objective: The aim of this study was to determine the incidence and prevalence of psoriatic arthropathy and to point out the problem of their occurrence in a sample of patients diagnosed with psoriasis. Methods: 109 patients with diagnosed psoriasis and psoriatic arthropathy, took part in the survey. The average age of patients was 48,85±10,11. We analyzed the incidence and prevalence of the psoriatic arthropathy occurrence for the patients with psoriasis. Results: Psoriatic arthropathy registered with patients were those with arthritic changes on: sacroiliac joints with 24 (22,02%) patients, 19 (79,17%) male and 5 (20,83%) female (p<0,001); spine with 11 (10,09%) patients, 6 (54,56%) male and 5 (45,45%) female (p=0,578); peripheral joints with 74 (67,89%) patients, 33 (44,59%) male and 41 (55,41%) female (p<0,01). When comparing the symptoms, most of the patients (63,30%) skin changes were represented before arthritis, for 27,52% patients arthritis preceded the skin changes, and for 9,17% patients the changes were simultaneous, Conclusion: Psoriatic arthropathy occurs more often in median age (31 to 50 years old) and it is more common for men than women. For most patient’s psoriatic skin changes preceded joints affection, with the most common ones being polyarthritis.
目的:本研究的目的是确定银屑病关节病的发病率和患病率,并指出其在诊断为银屑病的患者样本中发生的问题。方法:对109例诊断为银屑病及银屑病关节病的患者进行调查。患者平均年龄48、85±10、11岁。分析银屑病患者银屑病性关节病的发病率和患病率。结果:银屑病关节病患者以骶髂关节关节炎改变为主,其中男性19例(79.17%),女性5例(20.83%)(p< 0.001);脊柱11例(10.09%),男性6例(54.56%),女性5例(45.45%)(p= 0.578);外周关节74例(67.89%),男性33例(44.59%),女性41例(55.41%)(p< 0.01)。比较症状时,大多数患者(63,30%)皮肤变化出现在关节炎之前,27,52%的患者皮肤变化发生在关节炎之前,9,17%的患者皮肤变化同时发生。结论:银屑病关节病多见于中位年龄(31 ~ 50岁),男性多于女性。大多数银屑病患者的皮肤变化先于关节病变,最常见的是多发性关节炎。
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引用次数: 0
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International Journal of Medical Reviews and Case Reports
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