{"title":"ICPMS based multiplexed bioassay: Principles, approaches and progresses","authors":"Ziyan Li, Rui Liu, Yi Lv","doi":"10.1080/05704928.2021.1918703","DOIUrl":null,"url":null,"abstract":"Abstract Recent developments in multiplex bioassay around the theme of precision diagnostics have gained great focus. Inductively coupled plasma mass spectrometry (ICPMS) is emerging as a powerful platform for multiplex bioassay due to its high sensitivity, wide dynamic range, particularly its reliable multiplex sensing ability. This review discusses the progress being made in the multiplex bioassay applicating ICPMS, mainly emphasizes on varieties of biomarkers and methodological innovations. Also, we summarized limitations and proposed prospects to shed new light on the emergence of more powerful and application-oriented analytical methods.","PeriodicalId":8100,"journal":{"name":"Applied Spectroscopy Reviews","volume":"53 5 1","pages":"39 - 64"},"PeriodicalIF":5.4000,"publicationDate":"2021-05-12","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"6","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Applied Spectroscopy Reviews","FirstCategoryId":"92","ListUrlMain":"https://doi.org/10.1080/05704928.2021.1918703","RegionNum":2,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"INSTRUMENTS & INSTRUMENTATION","Score":null,"Total":0}
引用次数: 6
Abstract
Abstract Recent developments in multiplex bioassay around the theme of precision diagnostics have gained great focus. Inductively coupled plasma mass spectrometry (ICPMS) is emerging as a powerful platform for multiplex bioassay due to its high sensitivity, wide dynamic range, particularly its reliable multiplex sensing ability. This review discusses the progress being made in the multiplex bioassay applicating ICPMS, mainly emphasizes on varieties of biomarkers and methodological innovations. Also, we summarized limitations and proposed prospects to shed new light on the emergence of more powerful and application-oriented analytical methods.
期刊介绍：
Applied Spectroscopy Reviews provides the latest information on the principles, methods, and applications of all the diverse branches of spectroscopy, from X-ray, infrared, Raman, atomic absorption, and ESR to microwave, mass, NQR, NMR, and ICP. This international, single-source journal presents discussions that relate physical concepts to chemical applications for chemists, physicists, and other scientists using spectroscopic techniques.
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