Treatment gaps, 1-year readmission and mortality following myocardial infarction by diabetes status, sex and socioeconomic disadvantage

J. Morton, J. Ilomäki, S. Wood, J. Bell, Q. Huynh, D. Magliano, J. Shaw
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引用次数: 3

Abstract

Aims We evaluated variation in treatment for, and outcomes following, myocardial infarction (MI) by diabetes status, sex and socioeconomic disadvantage. Methods We included all people aged ≥30 years who were discharged alive from hospital following MI between 1 July 2012 and 30 June 2017 in Victoria, Australia (n=43 272). We assessed receipt of inpatient procedures and discharge dispensing of cardioprotective medications for each admission, as well as 1-year all-cause, cardiovascular, and MI readmission rates and 1-year all-cause mortality. Results Risk of all-cause (HR: 1.22 (1.19–1.26)), cardiovascular (1.29 (1.25–1.34)), MI (1.52 (1.43–1.62)) and heart failure readmission (1.62 (1.50–1.75)) and mortality (1.18 (1.11–1.26)) were higher in people with diabetes. Males and people in more disadvantaged areas were at increased risk of readmission and mortality following MI. People with diabetes (vs without) were more likely to receive coronary artery bypass grafting (CABG) but less likely to receive percutaneous coronary intervention (PCI) during, or within 30 days of, their index admission. Females were less likely to receive either (eg, 87% of males with a STEMI received PCI or CABG vs 70% of females), and people in more disadvantaged areas were less likely to receive PCI. People with diabetes, males and people in more disadvantaged areas were more likely to be dispensed cardioprotective medications at or within 90 days of discharge. Conclusions Following an MI, people with diabetes and males had poorer outcomes but received more intensive cardiovascular treatments. However, socioeconomic disadvantage was associated with both less intensive inpatient treatment and poorer outcomes.
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与糖尿病状况、性别和社会经济劣势相关的治疗缺口、心肌梗死后1年再入院率和死亡率
目的:我们评估糖尿病状况、性别和社会经济劣势对心肌梗死(MI)治疗和预后的影响。方法我们纳入了2012年7月1日至2017年6月30日期间在澳大利亚维多利亚州因心肌梗死而活着出院的所有年龄≥30岁的患者(n=43 272)。我们评估了每次住院患者的住院手续和出院时心脏保护药物的分配情况,以及1年全因、心血管和心肌梗死再入院率和1年全因死亡率。结果糖尿病患者的全因风险(HR: 1.22(1.19-1.26))、心血管风险(HR: 1.29(1.25-1.34))、心肌梗死风险(HR: 1.52(1.43-1.62))、心力衰竭再入院风险(HR: 1.62(1.50-1.75))和死亡率(HR: 1.18(1.11-1.26))较高。男性和更贫困地区的人在心肌梗死后再入院和死亡的风险增加。糖尿病患者(与非糖尿病患者相比)更有可能接受冠状动脉旁路移植术(CABG),但在入院期间或入院后30天内接受经皮冠状动脉介入治疗(PCI)的可能性更低。女性接受这两种治疗的可能性都较低(例如,87%的STEMI男性接受PCI或CABG治疗,而女性为70%),更弱势地区的人接受PCI治疗的可能性也较低。糖尿病患者、男性和生活在更不利地区的人更有可能在出院后90天或90天内获得心脏保护药物。结论:心肌梗死后,糖尿病患者和男性的预后较差,但接受了更强化的心血管治疗。然而,社会经济劣势与住院治疗强度较低和预后较差有关。
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