Implication of sex-determing factors for gender disparity in liver cancer

Mycotoxins Pub Date : 2014-01-01 DOI:10.2520/MYCO.64.95
S. Murakami, F. Tashiro
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引用次数: 1

Abstract

sex-determining factors including Sry (sex determining region Y) and sex hormones play a crucial role in onset of male HCC and its conversion into malignant tumor via cancer stem cell (CSC). These findings may confer the useful information for development of promising chemoprevention and anti-cancer drugs against male HCC.
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肝癌性别差异的性别决定因素的意义
包括Sry(性别决定区Y)和性激素在内的性别决定因素在男性HCC的发病和通过癌症干细胞(CSC)向恶性肿瘤的转化中起着至关重要的作用。这些发现可能为开发针对男性HCC的化学预防和抗癌药物提供有用的信息。
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