Emergence Delirium in Paediatric Anaesthesia

A. Maruf, M. Kamal, M. Hassan
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Abstract

Emergence delirium(ED) in children is a well-documented clinical phenomenon with incidence rangingfrom 25 to 80%. It is characterized by confusion, mental irritability, disorientation, inconsolable crying,and thrashing. No single factor can identified as the cause of postoperative agitation, which shouldtherefore be considered a syndrome made up of biological, pharmacological, psychological and socialcomponents. Possible causes and risk factors include child’s personality, inhalation anaesthetics,surgery of head and neck, rapid awakening and pain. Many scales have been proposed to evaluate theincidence and severity of ED and a variety of scales are used in clinical practice and for researchpurposes in children. Preventive measures include the co-administration of propofol, midazolam, orfentanyl, but the risks associated with their use must be weighed against the self-limiting nature of ED.Once ED is established, the most common interventions are pharmacological. Treatment options areclam environment in recovery and with agents having sedative and analgesic effect,such as propofol,fentanyl, ketamine andalpha-2 receptor agonists (clonidine and dexmedetomidine). ED may increasethe incidence of new-onset postoperative maladaptive behavior changes such as general anxiety,night-time crying, bed wetting, general anxiety and loss of appetite for up to 14 days after surgery. Astandard diagnostic, preventable and treatable guideline should be required for adverse outcomes in thepaediatric populations. JBSA 2021; 34 (2) : 16-23
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小儿麻醉中的突发性谵妄
儿童突发性谵妄(ED)是一种有充分文献记载的临床现象,发病率从25%到80%不等。它的特点是精神错乱,精神烦躁,迷失方向,无法安慰的哭泣和殴打。没有单一因素可以确定为术后躁动的原因,因此应将其视为由生物学、药理学、心理和社会成分组成的综合征。可能的原因和危险因素包括儿童的性格、吸入性麻醉剂、头颈部手术、快速觉醒和疼痛。已经提出了许多量表来评估ED的发病率和严重程度,并且在临床实践和儿童研究中使用了各种量表。预防措施包括异丙酚、咪达唑仑和奥芬太尼的联合用药,但必须权衡与使用这些药物相关的风险与ED的自限性。一旦ED确定,最常见的干预措施是药物。治疗方案为镇静和镇痛药物,如异丙酚、芬太尼、氯胺酮和α -2受体激动剂(clonidine和右美托咪定)。ED可能会增加术后新发适应不良行为改变的发生率,如全身焦虑、夜间哭泣、尿床、全身焦虑和食欲不振,持续时间长达术后14天。儿科人群的不良后果需要标准的诊断、预防和治疗指南。JBSA 2021;34 (2): 16-23
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