{"title":"High blood pressure induced by the rivastigmine patch as an uncommon side effect","authors":"C. Huang, Chia Ming Chang, H. Tu","doi":"10.6890/IJGE.201912_13(4).0021","DOIUrl":null,"url":null,"abstract":"Among older adults, Alzheimer disease (AD) is a worldwide health problem that causes functional disorders in memory, cognition, learning, behavior, and attention. 3 Cholinergic neurons are deficient in patients with AD. Rivastigmine is a new-generation agent that compensates for the lack of acetylcholine secretion in AD. 5 The Food & Drug Administration approved the rivastigmine patch in July 2007. However, the adverse drug reactions that occur in less than 5% of cases clinically are less attractive. The changes in blood pressure and heart rate induced by cholinesterase inhibitor (ChEI) have rarely been described. We report a patient who exhibited cholinergic-associated symptoms of nausea, vomiting, and high blood pressure induced by the larger dose of rivastigmine patch.","PeriodicalId":50321,"journal":{"name":"International Journal of Gerontology","volume":"13 3 1","pages":"363-364"},"PeriodicalIF":0.3000,"publicationDate":"2019-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Journal of Gerontology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.6890/IJGE.201912_13(4).0021","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"GERIATRICS & GERONTOLOGY","Score":null,"Total":0}
引用次数: 0
Abstract
Among older adults, Alzheimer disease (AD) is a worldwide health problem that causes functional disorders in memory, cognition, learning, behavior, and attention. 3 Cholinergic neurons are deficient in patients with AD. Rivastigmine is a new-generation agent that compensates for the lack of acetylcholine secretion in AD. 5 The Food & Drug Administration approved the rivastigmine patch in July 2007. However, the adverse drug reactions that occur in less than 5% of cases clinically are less attractive. The changes in blood pressure and heart rate induced by cholinesterase inhibitor (ChEI) have rarely been described. We report a patient who exhibited cholinergic-associated symptoms of nausea, vomiting, and high blood pressure induced by the larger dose of rivastigmine patch.
期刊介绍:
The Journal aims to publish original research and review papers on all fields of geriatrics and gerontology, including those dealing with critical care and emergency medicine.
The IJGE aims to explore and clarify the medical science and philosophy in all fields of geriatrics and gerontology, including those in the emergency and critical care medicine. The IJGE is determined not only to be a professional journal in gerontology, but also a leading source of information for the developing field of geriatric emergency and critical care medicine. It is a pioneer in Asia.
Topics in the IJGE cover the advancement of diagnosis and management in urgent, serious and chronic intractable diseases in later life, preventive medicine, long-term care of disability, ethical issues in the diseased elderly and biochemistry, cell biology, endocrinology, molecular biology, pharmacology, physiology and protein chemistry involving diseases associated with age. We did not limit the territory to only critical or emergency condition inasmuch as chronic diseases are frequently brought about by inappropriate management of acute problems.