Formulation and Evaluation of Verdant Tablets Containing Saponin-Coalesced Silver Nanoparticles Got from Fenugreek Seed Extract

Abstract

: Presently, nanoparticles are in demand due to several applications. Commercially used metallic nanoparticles are usually comprised of synthetic chemicals. These chemicals are noxious and combustible. Current research had the objective to explore the advantages of nanoparticles using herbal material; hence, we developed silver nanoparticles of aqueous extract of Trigonellafoenum graecum (Fenugreek) seeds and formulated them into tablets. Fenugreek seeds contain steroidal sapogenins and are responsible for the reduction of blood cholesterol levels, control diabetes, enhance breast milk production, digestion aid, and helps in weight loss hence prepared formulation can be recommended in all the above cases. The pre-compression parameters evaluated for formulations are bulk density, tapped density, Carr’s index, Hausner’s ratio, and angle of repose, and the results are 0.16 gm/cc, 0.86 gm/cc, 14.16, ratio 1.13 and 32 ◦ , respectively; whereas post-compression parameters are weight variation, friability, hardness, thickness, and disintegration, and the results are 0.504 gm, 0.2%, 3.21 gm/cm 2 , 2.55 mm, and 7 min, respectively.