{"title":"COVID-19 Convalescents Exhibit Humoral Immunity to SARS-COV-2 Envelope (E) Protein","authors":"E. Orlova, I. Kondratov, O. Ogarkov","doi":"10.33647/2074-5982-18-3-32-36","DOIUrl":null,"url":null,"abstract":"In this work, we obtain a producer of the recombinant SARS-CoV-2 E protein and develop a system for its expression and purification in a soluble form. ELISA confirmed its antigenic properties. In COVID-19 convalescents, the level of IgG against the E protein was significantly increased in comparison with the control group of patients.","PeriodicalId":14837,"journal":{"name":"Journal Biomed","volume":"9 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2022-10-17","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal Biomed","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.33647/2074-5982-18-3-32-36","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
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Abstract
In this work, we obtain a producer of the recombinant SARS-CoV-2 E protein and develop a system for its expression and purification in a soluble form. ELISA confirmed its antigenic properties. In COVID-19 convalescents, the level of IgG against the E protein was significantly increased in comparison with the control group of patients.
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