Diagnostic parameters used in detecting of serious surgical soft tissue infection: Necrotizing fasciitis

L. Farhan
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Abstract

Soft tissue infection in surgery is rapidly progressive infection that caused by variety of bacteria and their exotoxins that ultimately lead to extensive damage and necrosis of deep tissue and fascia. When it occurs in susceptible patients it led to septicemia and septic shock. It occurs mainly in scrotum, pernium and lower limbs and among malnutrition debilitated person. The disease is of high mortality rate. Early identification using is important to unwanted surgical consequence. Aim of study: To focus on the cause and diagnosis of serious soft tissue infection using laboratory investigations. Material and method: The study include (626) patients, (378) male and (248), Age (19-67) years. The study was done in department of General surgery in Al –Ramadi hospital ( July 2008-July 2018). Samples of the study was collected from patients come to hospital suffered from Necrotizing fasciitis. These patients undergoing clinical, radiographical examination and laboratory investigations. Samples of tissue are collected for bacterial culture and send to laboratory for bacterial identification and antibiotic sensitivity. X-ray and CT were used for examination of the area. Blood samples were also collected and send to laboratory for complete blood examination. Results: The statistical results indicate that the severe cases is associated with lowest mean value of WBC (7.1806±1.95788), and lowest mean value of hemoglobin (6.9260±2.25653) and highest serum level of creatinine (145.9758±2.33841), glucose (13.8547±1.71067) and lowest serum sodium (94.0986±.22220) in comparison with control group. The mean difference is significant at 0.05 level (P<0.05). Conclusion: Necrotising soft tissue infection is a serious fatal condition. Focusing on the cause of such condition of is important to start the early treatment to avoid the mortality. *Correspondence to: Liqaa Shallal Farhan, M.Sc, B.D.S, Maxillofacial Surgery, Dentistry College, Anbar University, Iraq, E-mail: liqaa.shallal@gmail.com
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严重外科软组织感染的诊断参数:坏死性筋膜炎
手术软组织感染是由多种细菌及其外毒素引起的快速进行性感染,最终导致深部组织和筋膜的广泛损伤和坏死。当它发生在易感患者时,可导致败血症和感染性休克。主要发生于阴囊、阴部、下肢及营养不良者。这种病的死亡率很高。早期识别是避免不良手术后果的重要手段。目的:探讨严重软组织感染的病因及诊断方法。材料与方法:纳入626例患者,其中男性378例,男性248例,年龄19-67岁。该研究于2008年7月至2018年7月在Al -Ramadi医院普通外科完成。本研究的样本来自于因坏死性筋膜炎而入院的患者。这些患者正在接受临床、放射检查和实验室检查。收集组织样本进行细菌培养,并送到实验室进行细菌鉴定和抗生素敏感性测试。使用x线和CT检查该区域。同时亦采集血液样本送化验所作全面血液检查。结果:与对照组相比,重症患者WBC平均值最低(7.1806±1.95788),血红蛋白平均值最低(6.9260±2.25653),血清肌酐水平最高(145.9758±2.33841),血糖水平最高(13.8547±1.71067),血清钠水平最低(94.0986±0.22220)。平均差异在0.05水平上显著(P<0.05)。结论:软组织坏死性感染是一种严重的致命性疾病。重视病因,及早治疗,避免死亡是十分重要的。*通讯:Liqaa Shallal Farhan,伊拉克安巴尔大学牙科学院颌面外科理学硕士,理学博士,E-mail: liqaa.shallal@gmail.com
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