Maria Rą, El-Toukhy Ak, El-Shamy Am, Mahmoud Ha, Rizk Fh, Yousef Aly H, Nabo Mmh, Abdel-Ghafar Mt, Mabrouk Mm, Baiomy N, Ahmed Naser Zoghbi, E. Sm, Abdel-Latif Hm
{"title":"Obesity-induced oxidative stress enhances psychosomatic manifestations of premenstrual tension syndrome: Towards better therapeutic outcomes using combined treatments","authors":"Maria Rą, El-Toukhy Ak, El-Shamy Am, Mahmoud Ha, Rizk Fh, Yousef Aly H, Nabo Mmh, Abdel-Ghafar Mt, Mabrouk Mm, Baiomy N, Ahmed Naser Zoghbi, E. Sm, Abdel-Latif Hm","doi":"10.15761/tim.1000283","DOIUrl":"https://doi.org/10.15761/tim.1000283","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"80060233","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
S. Nikose, Devashree Nikose, Aditya Kekatpure, A. Awasthi, Shashank Jain, V. Kumbhre
Abbreviations: SARS-CoV : Severe acute respiratory syndrome corona virus; COVID-19 : Coronavirus disease 19; FDA : Food and drug administration; RNA : Ribonucleic acid; CP : Convalescent plasma; IU: International units; IV : Intravenous; CM : Chinese medicines/ medications; MAPK: Mitogen-activated protein kinase; PI3K : Class I phosphoinositide 3-kinase isoforms; mTOR : Mammalian Target of Rapamycin kinase/mechanistic Target of Rapamycin; SGK1 : Serine/ threonine-protein kinase; IL- 6R : Interleukin 6 receptor also known as CD126 (Cluster of Differentiation 126); AKG : Alkylglycerols (AKGs); TGF-β: Transforming growth factor-beta (TGF-β); EMT : Epithelial to mesenchymal transition; CQ: Chloroquine; HCQs : Hydroxychloroquines; MRSA : Methicillin-Resistant Staphylococcus aureus; Μm : Micrometer; mg: Milligrams; WHO : World health organization; SLAM: Signaling lymphocytic activation molecule; Vero: Verda Reno which means "green kidney" in Esperanto; pCXN2 : Vero cells with a vector plasmid; pCAG-Hslam : Expression plasmid encoding the human signaling lymphocytic activation molecule. Abstract Amidst the mid of December 2019, a novel coronavirus surfaced in the Wuhan region of China causing outbreaks of respiratory diseases along with assuming a pandemic proportion throughout the world due to its incredibly high airborne dissemination potential. Owing to the lack of efficient and specific treatments and the need to contain the epidemic”, alternative therapies including herbal and Phyto medications, Chinese drugs, convalescent plasma therapy, and vitamin C and D were relied upon for the management of this SARS-CoV pandemic. Drug repurposing and repositioning strategies were also adopted. These alternative therapies may set the stage towards a supplemental alternative and all-inclusive treatment of COVID-19 till a safe, tested and long-lasting protection via a vaccine becomes available for public use.
缩写:SARS-CoV:严重急性呼吸综合征冠状病毒;COVID-19:冠状病毒病19;FDA:食品和药物管理局;RNA:核糖核酸;CP:恢复期血浆;IU:国际单位;IV:静脉注射;CM:中药/药物;MAPK:丝裂原活化蛋白激酶;PI3K: I类磷酸肌肽3-激酶亚型;mTOR:哺乳动物雷帕霉素激酶靶点/雷帕霉素机制靶点SGK1:丝氨酸/苏氨酸蛋白激酶;IL- 6R:白细胞介素6受体，又称CD126 (Cluster of Differentiation 126);AKG:烷基甘油(AKGs);TGF-β:转化生长因子-β;EMT:上皮向间充质转化;CQ:氯喹;HCQs:羟氯喹;MRSA:耐甲氧西林金黄色葡萄球菌;Μm:千分尺;mg:毫克;卫生组织:世界卫生组织;SLAM:信号淋巴细胞活化分子;Vero: Verda Reno，在世界语中的意思是“绿肾”;pCXN2:带载体质粒的Vero细胞;pCAG-Hslam:编码人淋巴细胞信号活化分子的表达质粒。2019年12月中旬，一种新型冠状病毒在中国武汉地区出现，引发了呼吸道疾病的爆发，由于其极高的空气传播潜力，在全球范围内占据了大流行的比例。由于缺乏有效和特异性的治疗方法，并且需要“控制疫情”，因此依靠包括草药和植物药物、中药、恢复期血浆治疗以及维生素C和D在内的替代疗法来管理这次SARS-CoV大流行。还采取了药物再利用和重新定位策略。这些替代疗法可能为COVID-19的补充替代和全包治疗奠定基础，直到通过疫苗提供安全、经过测试和持久的保护，供公众使用。
{"title":"Does complementary and alternative therapy work for SARS-CoV-2 (COVID-19)?","authors":"S. Nikose, Devashree Nikose, Aditya Kekatpure, A. Awasthi, Shashank Jain, V. Kumbhre","doi":"10.15761/TIM.1000256","DOIUrl":"https://doi.org/10.15761/TIM.1000256","url":null,"abstract":"Abbreviations: SARS-CoV : Severe acute respiratory syndrome corona virus; COVID-19 : Coronavirus disease 19; FDA : Food and drug administration; RNA : Ribonucleic acid; CP : Convalescent plasma; IU: International units; IV : Intravenous; CM : Chinese medicines/ medications; MAPK: Mitogen-activated protein kinase; PI3K : Class I phosphoinositide 3-kinase isoforms; mTOR : Mammalian Target of Rapamycin kinase/mechanistic Target of Rapamycin; SGK1 : Serine/ threonine-protein kinase; IL- 6R : Interleukin 6 receptor also known as CD126 (Cluster of Differentiation 126); AKG : Alkylglycerols (AKGs); TGF-β: Transforming growth factor-beta (TGF-β); EMT : Epithelial to mesenchymal transition; CQ: Chloroquine; HCQs : Hydroxychloroquines; MRSA : Methicillin-Resistant Staphylococcus aureus; Μm : Micrometer; mg: Milligrams; WHO : World health organization; SLAM: Signaling lymphocytic activation molecule; Vero: Verda Reno which means \"green kidney\" in Esperanto; pCXN2 : Vero cells with a vector plasmid; pCAG-Hslam : Expression plasmid encoding the human signaling lymphocytic activation molecule. Abstract Amidst the mid of December 2019, a novel coronavirus surfaced in the Wuhan region of China causing outbreaks of respiratory diseases along with assuming a pandemic proportion throughout the world due to its incredibly high airborne dissemination potential. Owing to the lack of efficient and specific treatments and the need to contain the epidemic”, alternative therapies including herbal and Phyto medications, Chinese drugs, convalescent plasma therapy, and vitamin C and D were relied upon for the management of this SARS-CoV pandemic. Drug repurposing and repositioning strategies were also adopted. These alternative therapies may set the stage towards a supplemental alternative and all-inclusive treatment of COVID-19 till a safe, tested and long-lasting protection via a vaccine becomes available for public use.","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74781337","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Adapted physical activity to treat chronic disease: A literature review of obstacles to prescription and compliance","authors":"V. Tchirkov, Romaine Didierjean, Laura Schuft","doi":"10.15761/tim.1000274","DOIUrl":"https://doi.org/10.15761/tim.1000274","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"89420608","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Ángel Verner Venegas Vera, María Juana Pérez López, Carolina Aguilar Martínez, Felipe Ericel Hernández Arellanes, Cristhian Muñoz Menjivar, L. F. Lizardi Gómez, Josué Antonio Ortega Pacheco, Hugo Gerardo Quezada Bucio, Claudio Francisco Mundo Gómez, Gates B. Colbert, Juan Carlos H Hernández Rivera, R. Paniagua Sierra
{"title":"Patency of trans-lumbar and intra-atrial catheters in patients with end stage renal disease and end stage vascular access failure","authors":"Ángel Verner Venegas Vera, María Juana Pérez López, Carolina Aguilar Martínez, Felipe Ericel Hernández Arellanes, Cristhian Muñoz Menjivar, L. F. Lizardi Gómez, Josué Antonio Ortega Pacheco, Hugo Gerardo Quezada Bucio, Claudio Francisco Mundo Gómez, Gates B. Colbert, Juan Carlos H Hernández Rivera, R. Paniagua Sierra","doi":"10.15761/tim.1000267","DOIUrl":"https://doi.org/10.15761/tim.1000267","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87883987","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
Berta Torres-Novellas, R. Guayta-Escolies, P. Rius, Amparo Castellà, P. Gascón, P. Modamio, Eduardo L. Mariño
{"title":"A study protocol for an experimental study for a pharmaceutical care programme to improve chronic complex disease management: PCAF programme","authors":"Berta Torres-Novellas, R. Guayta-Escolies, P. Rius, Amparo Castellà, P. Gascón, P. Modamio, Eduardo L. Mariño","doi":"10.15761/tim.1000262","DOIUrl":"https://doi.org/10.15761/tim.1000262","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"88432386","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Differential effects of Platelet-derived growth factor on c-Jun-N-Terminal Kinase and AP-1/ NF-kB activities in human glioblastoma T98G cells","authors":"E. Parra, Víctor Rojas, J. Ferreira, P. Hecht","doi":"10.15761/tim.1000277","DOIUrl":"https://doi.org/10.15761/tim.1000277","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"82666274","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Manifesto for research on intradermal vaccines proposed by the Italian Society of Mesotherapy","authors":"M. M., R. D, D. R., P. T., Maggiori E, M. A","doi":"10.15761/tim.1000281","DOIUrl":"https://doi.org/10.15761/tim.1000281","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"74547538","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
José Luis Mosso Vázquez, Carlos Jesús Castañeda González, Dejanira Mosso Lara, Julián Sánchez Cortázar, R.A. Carrillo Mezo, Oscar René Marrufo Meléndez, Mayra Ortiz Givaundan, Yolanda Tovar Ortega, B. Wiederhold, M. Wiederhold, I. Miller
Objective . Demonstrate remarkable improving behavior and mood as well
目标。表现出显著的行为和情绪改善
{"title":"Resting State fMRI, before and after Scottish rite freemasonry initiation ceremony to get entered apprentice degree in a female","authors":"José Luis Mosso Vázquez, Carlos Jesús Castañeda González, Dejanira Mosso Lara, Julián Sánchez Cortázar, R.A. Carrillo Mezo, Oscar René Marrufo Meléndez, Mayra Ortiz Givaundan, Yolanda Tovar Ortega, B. Wiederhold, M. Wiederhold, I. Miller","doi":"10.15761/tim.1000271","DOIUrl":"https://doi.org/10.15761/tim.1000271","url":null,"abstract":"Objective . Demonstrate remarkable improving behavior and mood as well","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"87919163","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Pathophysiology of Bone and Cardiac Involvement in Spondyloarthropathies: The indispensible value of magnetic resonance imaging","authors":"Mavrogeni Si, N. I, B. M., Kitas Gd","doi":"10.15761/tim.1000282","DOIUrl":"https://doi.org/10.15761/tim.1000282","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"81027480","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
{"title":"Interleukin 6 is a two-edged sword: a centerpiece in the immune response against the SARS-CoV-2","authors":"Bandar Ali Suliman","doi":"10.15761/tim.1000275","DOIUrl":"https://doi.org/10.15761/tim.1000275","url":null,"abstract":"","PeriodicalId":23337,"journal":{"name":"Trends in Medicine","volume":null,"pages":null},"PeriodicalIF":0.0,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":null,"resultStr":null,"platform":"Semanticscholar","paperid":"86797915","PeriodicalName":null,"FirstCategoryId":null,"ListUrlMain":null,"RegionNum":0,"RegionCategory":"","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":"","EPubDate":null,"PubModel":null,"JCR":null,"JCRName":null,"Score":null,"Total":0}
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