Neuromodulation – the future of diabetes treatments

Jonathan J. Waataja
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Abstract

have diabetes in the UK alone, and approximately 90% of these individuals have type 2 diabetes mellitus (T2DM). Patients with type 2 diabetes lose normal control of blood sugar levels, resulting in an overload of sugar in the blood, known as poor blood implementation of interventions such as medication, surgery, and dietary changes. For example, approximately 50% of type 2 diabetics do not take medications as prescribed. This is often due to the unwanted side effects of diabetic medications. Even the treatment options – GLP-1 receptor agonists – which improve glycaemic control are linked to kidney injury and severe nausea. Adherence to GLP-1 receptor agonist therapy is also a continuing problem, even with once-weekly injections. The urgent need for better and more effective treatments is an ongoing challenge in the research industry.
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神经调节——糖尿病治疗的未来
仅在英国就有大约90%的人患有2型糖尿病(T2DM)。2型糖尿病患者失去对血糖水平的正常控制,导致血糖在血液中过载,被称为不良血液实施干预措施,如药物、手术和饮食改变。例如,大约50%的2型糖尿病患者不按规定服药。这通常是由于糖尿病药物的不良副作用。即使是改善血糖控制的治疗选择——GLP-1受体激动剂——也与肾损伤和严重恶心有关。坚持GLP-1受体激动剂治疗也是一个持续的问题,即使每周一次注射。迫切需要更好、更有效的治疗方法是研究行业面临的一个持续挑战。
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