Stabilitas Whole Blood Control Tiga Level Yang Disimpan Pada Suhu 2-8oC Menggunakan Alat Hematology Analyzer

Adela Caesaria, Anik Handayati, Ayu Puspitasari
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Abstract

Quality assurance is important to ensure that the quality system runs properly and guarantees the results of laboratory tests, one of which is the inspection of control materials. The control material requirement is to have long stability, blood-like characteristics and low price. From these conditions, commercial control materials have a longer stability than fresh blood but are expensive. In practice, commercial control materials are still used even after the expiry date of the materials has passed. This is because the availability of materials is often delayed, the procurement of materials takes a long time and the price is relatively expensive. Therefore, this study aims to determine the stability of commercial whole blood control stored at 2-8 o C. This research is an experimental analytic study with a cross sectional research design. The sample in this study was commercial whole blood control with 3 levels, namely normal, low abnormally and abnormally high levels which were stored at 2-8 o C and checked every week for 10 weeks. Based on the test results obtained p-value for each parameter at all levels on the parameters of the number of erythrocytes, leukocyte count, hematocrit, hemoglobin and platelet count. Based on the results, it can be concluded that there is no change in the stability of whole blood control with storage for 10 weeks at a temperature of 2-8 o C on the parameters of abnormally low and normal leukocyte count levels, abnormally low and abnormally high hematocrit levels, and all levels on the parameters of leukocyte count, hemoglobin and platelet count. Meanwhile, in the normal level of hematocrit parameters and abnormally high leukocyte count, there is a change in stability.
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质量保证是确保质量体系正常运行和保证实验室测试结果的重要手段,其中之一就是对控制材料的检查。控制材料的要求是具有长时间的稳定性,血液般的特性和低廉的价格。在这些条件下,商业控制材料比新鲜血液具有更长的稳定性,但价格昂贵。在实践中,即使已过了管制物料的有效期,商业管制物料仍会继续使用。这是因为材料的可用性往往会延迟,材料的采购需要很长时间,价格也相对昂贵。因此,本研究旨在确定商品全血对照在2-8℃下储存的稳定性。本研究采用横断面研究设计的实验分析研究。本研究样本为商业全血对照,正常、低异常、异常高3个水平,保存于2-8℃,每周检测一次,持续10周。根据试验结果得到红细胞数、白细胞计数、红细胞比容、血红蛋白和血小板计数各参数在各级的p值。综上所述,在2 ~ 8℃温度下保存10周的全血控制在白细胞计数异常低和正常、红细胞压积异常低和异常高、白细胞计数、血红蛋白和血小板计数各水平参数的稳定性均无变化。同时,在红细胞压积参数正常水平和白细胞计数异常高的情况下,稳定性发生变化。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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