O. Henriksen, P. Christiansen, H. Larsson, M. Stubgaard
{"title":"In vivo quantitative 1H-MRS of metabolites in the brain using water as internal standard","authors":"O. Henriksen, P. Christiansen, H. Larsson, M. Stubgaard","doi":"10.1109/IEMBS.1992.5762122","DOIUrl":null,"url":null,"abstract":"A method is presented for in vivo quantification of some brain metabolites detected by water suppressed volume selected proton MR-spectroscopy using the unsaturated water signal as internal standard. In vitro as well as studies on 17 healthy volunteers were carried out. The results indicated that the concentration of N-acetyl aspartate, creatine + phosphocreatine, choline containing compounds and inositols could be determined reasonably with this first order approximation.","PeriodicalId":6457,"journal":{"name":"1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","volume":"1 1","pages":"1964-1965"},"PeriodicalIF":0.0000,"publicationDate":"1992-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"1992 14th Annual International Conference of the IEEE Engineering in Medicine and Biology Society","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1109/IEMBS.1992.5762122","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
Abstract
A method is presented for in vivo quantification of some brain metabolites detected by water suppressed volume selected proton MR-spectroscopy using the unsaturated water signal as internal standard. In vitro as well as studies on 17 healthy volunteers were carried out. The results indicated that the concentration of N-acetyl aspartate, creatine + phosphocreatine, choline containing compounds and inositols could be determined reasonably with this first order approximation.
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