Clinical Study of Quyuhuazhuo on Reducing Blood Hypercoagulability of Malignant Tumors

Abstract

Objective: To investigate the clinical significance of Quyuhuazhuo on reducing blood stasis syndrome of malignant tumors (hypercoagulable state of blood). Methods: 60 malignant tumor patients with hypercoagulable state were randomly divided into treatment group and control group. In treatment group, 30 patients were treated with Quyuhuazhuo combined with chemotherapy. In control group, the other 30 patients received chemotherapy only. The clinical symptoms were observed. The changes of PLT (platelet), FIB (fibrinogen), PT (prothrombin time), APTT (activated partial thromboplastin time) and D-dimer were monitored dynamically before and after treatment. Result: The time of PT and APTT was prolonged significantly in treatment group compared with control group (P<0.05), and the value of PLT, FIB and D-dimer decreased significantly (P<0.05). Conclusion: The combined treatment of chemotherapy with Quyuhuazhuo can reduce the hypercoagulable state in malignant tumor patients.