Clinical impact of chronic obstructive pulmonary disease (COPD) verified by the COPD Assessment Test (CAT) can be associated with functional capacity

Maiara Almeida Aldá, Flávio Danilo Mungo Pissulin, S. Weber, Ricardo Beneti, M. Leite, F. Pacagnelli
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Abstract

The aim of this study was to investigate the impact of the different degrees of severity of ‘CAT’ in the functional capacity evaluated by the 6-minute walk test (6MWT). This is a cross-sectional study, which included spirometrically defined COPD patients, out of exacerbation period and with motor and cognitive skills necessary to perform the spirometry and the 6MWT and reply to the ‘CAT’ questionnaire. We sorted groups according to the clinical impact proposed by ‘CAT’: mild, moderate, severe and very severe. We included 66 COPD patients, with FEV1 (% pred) averages of 53.1 ± 21.9, 51.4 ± 14.1, 50.6 ± 12.8 and 46.4 ± 13.0, which corresponded to the clinical impact of ‘CAT’, respectively (p > 0.05). The highest ‘CAT’ score, observed on mild, moderate and severe clinical impact did not determine the shortest walking distance in the 6MWT (p 30 (very severe clinical impact) was associated with shorter walking distance in the 6MWT (p < 0.05). We found no negative correlation between ‘CAT’ and 6MWT (p = 0.0707 and r = -0.2479). ‘CAT’ was not associated to 6MWT.
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慢性阻塞性肺疾病(COPD)的临床影响经COPD评估试验(CAT)证实可与功能能力相关
本研究的目的是研究不同程度的“CAT”严重程度对6分钟步行测试(6MWT)评估的功能能力的影响。这是一项横断面研究,纳入了经肺活量测定定义的COPD患者,这些患者已过了加重期,具有进行肺活量测定和6MWT所需的运动和认知技能,并回答了CAT问卷。我们根据“CAT”提出的临床影响进行分组:轻度、中度、重度和极重度。我们纳入66例COPD患者,FEV1 (% pred)平均值分别为53.1±21.9、51.4±14.1、50.6±12.8和46.4±13.0,与“CAT”的临床影响相对应(p < 0.05)。在轻度、中度和重度临床影响中观察到的最高CAT评分并不能决定6MWT中最短的步行距离(p30(非常严重的临床影响)与6MWT中较短的步行距离相关(p < 0.05)。我们发现“CAT”与6MWT之间没有负相关(p = 0.0707, r = -0.2479)。' CAT '与6MWT无关。
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