Effect of lifestyle intervention holistic approach on blood glucose levels, health-related quality of life and medical treatment cost in type 2 diabetes mellitus patients

G. Kumari, Vikram Singh, Bimal Chhajer, A. Jhingan
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Abstract

Type 2 Diabetes Mellitus (T2DM) is a costly, lifestyle-related disorder, its management is very critical and challenging hence lifestyle intervention may a cornerstone in the reversal and management of T2DM. This study designed to assess the impact of lifestyle intervention holistic (LIH) Model on blood glucose levels (BGL), Health-Related Quality of Life (HRQOL), and medical treatment cost in T2DM patients. This prospective, quasi-experimental study was conducted among 224 T2DM patients in Delhi Diabetes Research Center (DDRC), New Delhi. The study participants were allocated into two groups-Lifestyle Intervention Counseling (LIC) group received lifestyle-based counseling through the LIH model while the Usual-care group received only standard treatment. Study outcomes were assessed at baseline, 3rd, 6th, and 12th month and data were analyzed through SPSS. Study results revealed that LIC participants had decreased in fasting blood glucose 0.26 mg dL (-4.37 to 4.89), blood glucose postprandial -70.16 mg dL (-85.15 to 55.16), HbA1C -2.82% (-5.26 to 0.37), medicine cost (p < 0.004), hospitalization cost (p < 0.011), and cost of surgery (p < 0.0005). A significant improvement also observed in HRQOL and adherence towards a holistic model in LIC group. The study concludes that lifestyle-based counseling and its adherence was cost-effective and significantly improves BGL, HRQoL, and medical treatment in T2DM patients.
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生活方式干预整体方法对2型糖尿病患者血糖水平、健康相关生活质量及医疗费用的影响
2型糖尿病(T2DM)是一种昂贵的生活方式相关疾病,其管理非常关键且具有挑战性,因此生活方式干预可能是T2DM逆转和管理的基石。本研究旨在评估生活方式干预整体模型(LIH)对T2DM患者血糖水平(BGL)、健康相关生活质量(HRQOL)和医疗费用的影响。这项前瞻性、准实验研究在新德里糖尿病研究中心(DDRC)的224例T2DM患者中进行。研究参与者被分为两组,生活方式干预咨询组(LIC)通过LIH模型接受基于生活方式的咨询,而常规护理组只接受标准治疗。在基线、第3、第6和第12个月评估研究结果,并通过SPSS对数据进行分析。研究结果显示,LIC参与者空腹血糖下降0.26 mg dL(-4.37至4.89),餐后血糖下降-70.16 mg dL(-85.15至55.16),糖化血红蛋白下降-2.82%(-5.26至0.37),药物费用(p < 0.004),住院费用(p < 0.011),手术费用(p < 0.0005)。LIC组的HRQOL和对整体模型的依从性也有显著改善。该研究得出结论,基于生活方式的咨询及其依从性具有成本效益,可显著改善2型糖尿病患者的BGL、HRQoL和药物治疗。
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