THE PECULIARITIES OF DETECTION AND DIAGNOSIS OF TUBERCULOSIS IN CHILDREN AND ADOLESCENTS

N. Pravada, A.M. Budritskiy, V.A. Seryogina
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引用次数: 2

Abstract

Objectives. To assess the peculiarities of diagnosis and clinical course of tuberculosis in children and adolescents. Material and methods. Retrospective analysis of outpatient records of children and adolescents with tuberculosis in Vitebsk region during the period from 2016 to 2020 was made. Results. In the tuberculous disease structure in children and adolescents, pulmonary tuberculosis (infiltrative pulmonary tuberculosis) prevails. In the majority of cases, tuberculosis was diagnosed during adolescence. Almost all of the sick had close family contact with tuberculosis patients. The medical risk group included 25% of patients. In patients with infiltrative pulmonary tuberculosis, symptoms and changes in the total blood count were observed only in the phase of disintegration and seeding. Bacteriological excreters made up 75% of cases. More than half of children and adolescents with tuberculosis had multidrug resistance of mycobacterium tuberculosis. Immunodiagnosing plays an important role in the detection of tuberculosis in children and adolescents. Among the sick children, only extrapulmonary forms of tuberculosis were recorded. Conclusions. Most often, tuberculosis in children and adolescents affects the respiratory organs and is asymptomatic or oligosymptomatic. 75% of patients were bacteria discharging persons, more than half of them having multidrug resistance. Family contact is of great importance in tuberculosis in children and adolescents. Doctors of all specialties need to have phthisiatric alertness in relation to patients with diseases of various localization resistant to nonspecific therapy, especially to persons with chronic diseases and to those who contact with patients suffering from tuberculosis. In case of ineffective antibiotic therapy, it is necessary to take the material for the study and verification of tuberculous infection and to carry out immunodiagnosing of tuberculosis.
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儿童和青少年肺结核的检测和诊断特点
目标。评估儿童和青少年结核病的诊断特点和临床病程。材料和方法。回顾性分析2016 - 2020年维捷布斯克地区儿童和青少年结核病门诊记录。结果。在儿童和青少年的结核病结构中,以肺结核(浸润性肺结核)为主。在大多数病例中,结核病是在青春期被诊断出来的。几乎所有患者都与结核病患者有密切的家庭接触。医疗风险组包括25%的患者。在浸润性肺结核患者中,症状和总血细胞计数的变化仅在解体和播种期观察到。细菌排泄物占病例的75%。半数以上的儿童和青少年结核病患者存在结核分枝杆菌多药耐药。免疫诊断在儿童和青少年结核病的检测中起着重要作用。在患病儿童中,仅记录了肺外结核。结论。大多数情况下,儿童和青少年的结核病影响呼吸器官,无症状或无症状。75%的患者为细菌排出者,其中半数以上存在多药耐药。家庭接触对儿童和青少年的结核病非常重要。所有专业的医生都需要对患有非特异性治疗的各种局部疾病的患者,特别是慢性病患者和与结核病患者接触的患者保持警惕。在抗生素治疗无效的情况下,有必要采取材料对结核感染进行研究和验证,并对结核进行免疫诊断。
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