Aortic root operation for aortic aneurysm: Valve replacement versus valve sparing procedures

Yousry El-Saied Rizk , Ibrahim Mohammed Kasab , Mahmoud Mohammed Ghalwash , Ahmed Mohammed Farag , Ramadan Ibrahim Ouf , Loay Aly Aljunaidy
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Abstract

Background

Aortic root replacement (Bentall operation) or Aortic valve sparing (David operation) are alternative surgical techniques for the treatment of aortic root aneurysm. The aim of the current study was to compare our 30-days mortality, post-operative care and complications associated with both procedures.

Methods

From January 2015 to December 2017, 45 consecutive patients (40 men; 88.9%), with mean age 43.2 ± 6.55 years underwent either Bentall operation (Group A: 30 patients; 66.7%) or David operation (Group B: 15 patients; 33.3%); according to surgeons' preference or expertise.

Group A patients were significantly older (47.1 ± 7.6 vs. 39.3 ± 5.5 years; P = 0.001), more hypertensive (10 patients; 33.3% vs. none; P = 0.019), had higher serum creatinine level (1.3 ± 0.28 vs. 39.3 ± 5.5 vs. 1.07 ± 0.12 mg/dl; P = 0.004), larger LVEDD (6.03 ± 0.4 vs. 5.40 ± 0.16 cm; P < 0.001) and lower EF% (56.6 ± 6.31 vs. 61.3 ± 3.51; P = 0.011) but needed shorter aortic cross clamp (101.8 ± 19.9 vs. 200 ± 16.9 min; P = 0.011) and bypass times (151.68 ± 17.2 vs. 266.6 ± 25.8 min; P < 0.001); compared to Group B.

Results

Overall 30-day mortality was 6.7% in both groups: 2 patients in Group A and 1 patient in Group B. Mortalities were significantly older (54.3 ± 7.23 vs. 43.9 ± 7.6 years; P = 0.025), had larger aortic root (71.6 ± 1.31 vs. 61.2 + 0.78 cm: P = 0.037) and left ventricular end diastolic diameters (6.37 ± 0.68 vs. 5.79 ± 0.44 cm; P < 0.038), needed prolonged mechanical ventilation (51.67 ± 24.39 vs. 92.33 ± 19.66 h; P = 0.007) and ICU stay (5.07 ± 1.98 vs. 8.33 ± 1.53 days; P = 0.008); compared to survivors. Group B patients had significantly longer aortic cross clamp and bypass times but showed Although 4 group B patients showed severe residual aortic regurge, compared to none in Group A (P = 0.23), yet. Other hospital complications were equally comparable.

Conclusion

Factors affecting our 30-days mortality were related to the severity of the disease. Both procedures could be valid alternatives, yet more cases of residual aortic regurge are expected with David operation, especially in the early learning curve.

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主动脉根部手术治疗动脉瘤:瓣膜置换术与保留瓣膜手术
背景:主动脉根置换术(Bentall手术)或保留主动脉瓣(David手术)是治疗主动脉根动脉瘤的可选手术技术。本研究的目的是比较两种手术的30天死亡率、术后护理和并发症。方法2015年1月至2017年12月,连续45例患者(男性40例;88.9%),平均年龄43.2 ± 6.55岁(A组:30例;66.7%)或David手术(B组:15例;33.3%);根据外科医生的喜好或专业知识。A组患者明显老年化(47.1 ± 7.6 vs. 39.3 ± 5.5岁;P = 0.001),高血压患者较多(10例;33.3% vs. 0;P = 0.019),血清肌酐水平较高(1.3 ±0.28 vs 39.3  ±  5.5和1.07±0.12  mg / dl;P = 0.004),LVEDD更大(6.03 ±  0.4和5.40±0.16  厘米;P & lt; 0.001)和低EF %( 56.6±6.31 vs 61.3  ± 3.51;P = 0.011),但需要更短的主动脉交叉钳(101.8 ± 19.9 vs 200 ± 16.9 min;P = 0.011)和旁路次数(151.68 ± 17.2 vs. 266.6 ± 25.8 min;P & lt; 0.001);结果两组患者30天总死亡率均为6.7%:A组2例,b组1例。两组患者的死亡率均显著老龄化(54.3±7.23∶43.9±7.6岁;P = 0.025),主动脉根部较大(71.6±1.31比61.2 + 0.78 cm: P = 0.037),左室舒张末期直径(6.37±0.68比5.79±0.44 cm;P & lt;0.038),需要延长机械通气时间(51.67±24.39∶92.33±19.66 h);P = 0.007)和ICU停留(5.07±1.98和8.33±1.53天;p = 0.008);与幸存者相比。虽然B组有4例患者出现严重的残余主动脉回流,而A组无一例(P = 0.23)。其他医院并发症同样具有可比性。结论影响30天死亡率的因素与疾病的严重程度有关。这两种方法都是有效的替代方法,但David手术预计会有更多的残余主动脉回流病例,特别是在早期学习曲线中。
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