Issues of Vaccination of SARS-CoV-2 Infection in Chronic Liver Diseases

E. Vinnitskaya, A. N. Ivanov, Y. Sandler
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Abstract

Vaccination of SARS-CoV-2 infection is an obvious and significant component of the fight against the COVID-19 pandemic. Vaccination of groups of patients with the weakened immunological response to the vaccine, such as patients with chronic liver diseases (CLD), is especially important. Due to constantly updated data, general practitioners may lose sight of the features of immunization of patients with CLD from the professional field of view. The purpose is to highlight current ideas on the immunization of patients with CLD of various etiologies, to consider possible risks of vaccination, to identify prospects for further research in this area. Conclusion. All patients with CLD, regardless of the etiology and stage of the disease, are recommended to be vaccinated against COVID-19, which reduces the risk of decompensation of both the main and concomitant chronic diseases, the onset of adverse outcomes and leads to the formation of collective immunity of the population
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慢性肝病中SARS-CoV-2感染的疫苗接种问题
预防SARS-CoV-2感染的疫苗接种是抗击COVID-19大流行的一个明显和重要组成部分。对疫苗免疫反应减弱的患者群体,如慢性肝病(CLD)患者接种疫苗尤为重要。由于数据的不断更新,全科医生可能会从专业的角度忽视CLD患者的免疫特征。目的是强调目前对各种病因的CLD患者进行免疫接种的想法,考虑接种疫苗的可能风险,并确定该领域进一步研究的前景。结论。所有CLD患者,无论病因和疾病分期如何,都建议接种COVID-19疫苗,这可以降低主要和伴随慢性疾病代偿失代偿的风险,减少不良后果的发生,并导致人群集体免疫的形成
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