Rituximab for Steroid Dependent Nephrotic Syndrome in Chinese Children

Ma Lt, L. Fiona, S. Euan, C. Norman, L. Iván, Tong Pak-chiu, Lai Wai-ming, Tse Niko
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Abstract

A retrospective 5-year review was performed on 11 children (mean age of 14.6 yrs (8.1-18 yrs), 8 boys and 3 girls) who had SD or FRNS from April 2009 to April 2014. All patients were in remission for at least 4 weeks before the start of Rituximab, and they received two doses of intravenous rituximab (500 mg). Their demographics (body weight, height, renal pathology, and number of relapses a year before rituximab, previous and concomitant medical treatment) were recorded.
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利妥昔单抗治疗中国儿童类固醇依赖性肾病综合征
回顾性分析了2009年4月至2014年4月期间发生SD或FRNS的11名儿童(平均年龄为14.6岁(8.1-18岁),其中男孩8名,女孩3名)。所有患者在开始使用利妥昔单抗前至少缓解4周,并接受两剂静脉注射利妥昔单抗(500 mg)。他们的人口统计数据(体重、身高、肾脏病理、利妥昔单抗前一年的复发次数、既往和伴随治疗)被记录下来。
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