{"title":"A Model-based Method for Measuring Autonomic Nerve Activity and Sensitivity","authors":"Xiang'ao Meng, Zhipei Huang, Jiankang Wu","doi":"10.1145/3375923.3375944","DOIUrl":null,"url":null,"abstract":"The measurement of autonomic nerve activity plays an important role in the diagnosis and treatment of various cardiovascular diseases. This paper presents a model-based method for measuring autonomic nerve activity and sensitivity. By non-invasively recording heart rate and blood pressure data of the subjects during the sit-to-stand experiment, we modeled the blood pressure-heart rate regulation system and solved personalized parameters. These personalized parameters were used to obtain the autonomic nerve activity and sensitivity of the subjects. We conducted experiments on 9 patients with refractory hypertension and 20 healthy people, and the results showed that there were significant differences in the sensitivity and activity of autonomic nerves.","PeriodicalId":20457,"journal":{"name":"Proceedings of the 2019 6th International Conference on Biomedical and Bioinformatics Engineering","volume":"54 1","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-11-13","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Proceedings of the 2019 6th International Conference on Biomedical and Bioinformatics Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1145/3375923.3375944","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
Abstract
The measurement of autonomic nerve activity plays an important role in the diagnosis and treatment of various cardiovascular diseases. This paper presents a model-based method for measuring autonomic nerve activity and sensitivity. By non-invasively recording heart rate and blood pressure data of the subjects during the sit-to-stand experiment, we modeled the blood pressure-heart rate regulation system and solved personalized parameters. These personalized parameters were used to obtain the autonomic nerve activity and sensitivity of the subjects. We conducted experiments on 9 patients with refractory hypertension and 20 healthy people, and the results showed that there were significant differences in the sensitivity and activity of autonomic nerves.
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