Water Mediated Synthesis of N′-Arylmethylene-4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide Library

M. Savant, A. M. Pansuriya, Chirag V. Bhuva, N. Kapuriya, Y. Naliapara
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Abstract

A novel two-step synthesis of 4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide has been developed. The library of N′-arylmethylene-4,5,6,7-tetrahydro-2H-indazole-3-carbohydrazide was generated by coupling of hydrazide to various aromatic and heterocyclic aldehydes in water media at ambient temperature with great flexibility regarding reaction time and yield.
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水介导合成N ' -芳基亚甲基-4,5,6,7-四氢- 2h -吲唑-3-碳酰肼文库
研究了一种新的两步法合成4,5,6,7-四氢- 2h -吲哚-3-碳酰肼的方法。在室温条件下,N ' -芳基亚甲基-4,5,6,7-四氢- 2h -吲唑-3-碳肼库是由肼与各种芳杂环醛在水介质中偶联而成,反应时间和产率具有很大的灵活性。
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