Gene therapy in the era of nanotechnology/a review of current data

Abstract

including drugs which can either be dissolved or encapsulated within them forming a nanoparticle and a Nano capsule respectively. The delivered therapeutic proteins or drugs act by altering defective proteins or genes in the patient’s cells. The size of the polymer nanoparticle could be tuned to enable these drugs and therapeutic protein to fit in. PNPs, like all nanoparticles are capable of regaining their size once inside the cell through the physiological change in pH. They are also great candidates for gene delivery, because they are highly stable and they offer controlled release of active ingredients.