Primary Cutaneous Large B Cell Lymphoma, Leg Type: Good Evolution of A Particular Location

Abstract

Primary cutaneous B-cell lymphomas are a heterogeneous group of rare clonal B-cell lymphoproliferative disorders with distinct clinicopathological features compared with nodal counterparts [1]. Primary cutaneous diffuse large B-cell lymphoma-leg type (PCLBCL-LT) is a rare subtype which constitutes only 4% [2]. They have a predilection to the leg (72%), advanced age of onset (mean age, 76 years), high Bcl-2 expression (85%) and frequent relapses with extracutaneous dissemination [10-20%]. We report a case we report the case of a young patient of 39 years old who consulted for a hummocky tumor in the back whose histology was in favor of lymphoma B-type leg, with good response to rituximab combined with doxorubicin, cyclophosphamide, vincristine, and prednison (R-CHOP).