Antiplatelet Therapy in Patients with Acute Coronary Syndrome: An Update

Adnan Bashar, Md. Harisul Hoque, M. Chowdhury, A. Hasan, Khurshed Ahmed
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Abstract

Antiplatelet therapy is the cornerstone in the treatment of acute coronary syndrome. Aspirin is the most widely used antiplatelet agent followed by P2Y12 inhibitors. Glycoprotein (GP) IIb-IIIa antagonists are also gaining popularity as an antiplatelet agents during peri-PCI period. This review article summarizes the indications, duration of dual antiplatelet therapy (DAPT) in ACS setting. Antiplatelet therapy in special situations like atrial fibrillation and thrombocytopenia are discussed here. Issues like switching between P2Y12 inhibitors and genetic testing of antiplatelet agents are also mentioned in this article University Heart Journal Vol. 17, No. 1, Jan 2021; 66-70
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急性冠脉综合征患者的抗血小板治疗:最新进展
抗血小板治疗是治疗急性冠脉综合征的基石。阿司匹林是应用最广泛的抗血小板药物,其次是P2Y12抑制剂。糖蛋白(GP) IIb-IIIa拮抗剂在pci围术期作为抗血小板药物也越来越受欢迎。本文就急性冠脉综合征(ACS)患者双重抗血小板治疗(DAPT)的适应症、疗程进行综述。在特殊情况下抗血小板治疗,如心房颤动和血小板减少在这里讨论。这篇文章也提到了P2Y12抑制剂和抗血小板药物基因检测之间的切换问题,《大学心脏杂志》第17卷,第1期,2021年1月;66 - 70
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