ESTIMATION OF THE POSSIBILITY OF WASTEWATER PURIFICATION FROM PHARMACEUTICAL PREPARATIONS BY RADIATION METHOD

Bulletin of the Saint Petersburg State Institute of Technology (Technical University) Pub Date : 2021-01-01 DOI:10.36807/1998-9849-2021-58-84-27-32

Zh. B. Lyutova, N. Orekhova, Anastasia A. Yamshchikova, I. V. Yudin

{"title":"ESTIMATION OF THE POSSIBILITY OF WASTEWATER PURIFICATION FROM PHARMACEUTICAL PREPARATIONS BY RADIATION METHOD","authors":"Zh. B. Lyutova, N. Orekhova, Anastasia A. Yamshchikova, I. V. Yudin","doi":"10.36807/1998-9849-2021-58-84-27-32","DOIUrl":null,"url":null,"abstract":"To assess the possibility of using radiation purification of aqueous solutions from contained pharmacological preparations by spectrophotometry, high-performance liquid chromatography and chemical analysis, the effect of the absorbed dose of ionizing radiation on the concentration of analytes in solutions was studied. The values of the radiation-chemical yield of destruction of the investigated pharmaceutical preparations, the formation of peroxide products of radiolysis were determined, and the values of absorbed doses sufficient for the complete decomposition of the substances under consideration were calculated. It was shown that at initial concentrations of ketoprofen of 1,1•10-4 M and diclofenac of 0,5•10-4 M, the values of absorbed doses required for their complete decomposition are 2,4 kGy and 0,85 kGy, respectively. The obtained values indicate the possibility of using radiation technology for the purification of aqueous solutions from those pharmaceutical preparations. Further research can clarify the necessary doses for sufficient destruction of various groups of drugs in concentrations found in wastewater","PeriodicalId":9467,"journal":{"name":"Bulletin of the Saint Petersburg State Institute of Technology (Technical University)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2021-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Bulletin of the Saint Petersburg State Institute of Technology (Technical University)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.36807/1998-9849-2021-58-84-27-32","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 0

Abstract

To assess the possibility of using radiation purification of aqueous solutions from contained pharmacological preparations by spectrophotometry, high-performance liquid chromatography and chemical analysis, the effect of the absorbed dose of ionizing radiation on the concentration of analytes in solutions was studied. The values of the radiation-chemical yield of destruction of the investigated pharmaceutical preparations, the formation of peroxide products of radiolysis were determined, and the values of absorbed doses sufficient for the complete decomposition of the substances under consideration were calculated. It was shown that at initial concentrations of ketoprofen of 1,1•10-4 M and diclofenac of 0,5•10-4 M, the values of absorbed doses required for their complete decomposition are 2,4 kGy and 0,85 kGy, respectively. The obtained values indicate the possibility of using radiation technology for the purification of aqueous solutions from those pharmaceutical preparations. Further research can clarify the necessary doses for sufficient destruction of various groups of drugs in concentrations found in wastewater

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

辐射法净化药物制剂废水可能性的评价

为了评估用分光光度法、高效液相色谱法和化学分析法对药理学制剂水溶液进行辐射净化的可能性，研究了电离辐射吸收剂量对溶液中分析物浓度的影响。测定了所研究的药物制剂的破坏的辐射化学产率，并计算了所研究的物质完全分解所需的吸收剂量值。结果表明，在酮洛芬的初始浓度为1,1•10-4 M和双氯芬酸的初始浓度为0,5•10-4 M时，它们完全分解所需的吸收剂量值分别为2.4 kGy和0.85 kGy。所得值表明了利用辐射技术从这些药物制剂中提纯水溶液的可能性。进一步的研究可以阐明对废水中各种浓度的药物进行充分破坏所需的剂量

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Bulletin of the Saint Petersburg State Institute of Technology (Technical University)

自引率

0.00%

发文量