Exploratory Laparotomy for Necrotizing Enterocolitis

Karla E. K. Wyatt, O. Olutoye
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Abstract

Necrotizing enterocolitis (NEC) is a severe inflammatory bowel disease that commonly affects premature infants. The pathogenesis is multifactorial and poorly understood, although certain risk factors have been identified. This disease, more commonly detected in premature infants with accompanying cardiac and pulmonary comorbid conditions, is associated with increased morbidity and mortality. Multiorgan system homeostasis becomes critical for the pediatric anesthesiologist when approaching medical and surgical interventions for affected patients. This chapter focuses on the population at risk for developing necrotizing enterocolitis, medical and surgical management, providing anesthesia care in the neonatal intensive care unit, as well as perioperative considerations and complications.
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剖腹探查术治疗坏死性小肠结肠炎
坏死性小肠结肠炎(NEC)是一种严重的炎症性肠病,通常影响早产儿。其发病机制是多因素的,尽管已经确定了某些危险因素,但对其了解甚少。这种疾病更常见于伴有心肺合并症的早产儿,与发病率和死亡率增加有关。多器官系统稳态对儿科麻醉师来说至关重要,因为他们需要对受影响的患者进行医疗和手术干预。本章重点介绍了发生坏死性小肠结肠炎的高危人群、医疗和手术管理、在新生儿重症监护病房提供麻醉护理以及围手术期注意事项和并发症。
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