Acute angle-closure glaucoma caused by topiramate–a drug complication that can lead to blindness

Abstract

Glaucoma is the commonest pattern of optic neuropathy characterized as a gradual loss of retinal ganglion cells (RGCs) as well as classic modifications to the retinal nerve fiber layer (RNFL) and optic nerve.1 Depending on the angle appearance at gonioscopy, it is classified as open-angle or closed-angle glaucoma.1 Likewise, if an underlying cause is established, the disease is perceived as secondary glaucoma.1 Considering closed-angle glaucoma characteristics, secondary drug-induced is a rare disease with a huge potential of perpetual visual loss.1