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Evolution of penetrating keratoplasty: the three eras, a brief historical review 穿透性角膜移植术的演变:三个时代,简要的历史回顾
Pub Date : 2023-10-05 DOI: 10.15406/aovs.2023.13.00447
Mahmoud R Amer, Hosam A Ibrahim Elzembely
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引用次数: 0
Comparison of post-op quality of vision of spheric IOL and aspheric hydrophilic acrylic yellow tinted intraocular lens implantation following phacoemulsification cataract surgery 晶状体人工晶状体与非晶状体亲水丙烯酸黄色人工晶状体植入术后视力质量比较
Pub Date : 2021-08-06 DOI: 10.15406/aovs.2021.11.00404
Safdar Hussain, A. Batool, S. Akram, Hina Manzoor, Ayesha Arshad
Purpose: To compare the post-op visual quality of spheric and aspheric acrylic yellow tinted intraocular lens following phacoemulsification cataract surgery. Place of study: Al-Majeed Laser Eye Hospital. Methods: Total 60 subjects (aged 40-65years) with age related mature cataracts were included. Data was assembled by non-probability convenient sampling technique at Al-Majeed Laser Eye Hospital. All patients presenting with mature cataract were include in this study without any other pathology and fundus abnormality. Pre and post-operative visual acuity was measured by using standard snellen visual acuity testing chart. For the purpose of accuracy repetitive values were taken for each patient. Post-operative vision was recorded one month followed by phacoemulsification. Comparisons was made between spheric and asphereic acrylic yellow tinted intraocular lens by applying (descriptive) statistics and paired sample t test for the analysis of results. Results: Quality of vision was compared post-operatively after implantation of aspheric hydrophilic acrylic IOL and spheric IOL in posterior chamber under the same phaco surgeon. All subjects after intra ocular implantation had better corrected visual acuity of 6/9 and more improved 6/6. There were found statistically differences in recorded visual acuity with aspheric yellow tinted iol implanation and spheric iol (p = 0.15) between the two types of intra-ocular lens. The mean, standard deviation, t-value found with spheric IOL were.1867, .18889, 2.517 respectively. However, of aspheric hydrophilic acrylic intra-ocular lens mean, standard deviation and t values found .800, .13493 and 2.5493 respectively. There was significant variance in statistics and quality of vision between the two types of lenses. Conclusions: This study concludes that post –operative improvement in quality of vision was better with aspheric hydrophilic yellow tinted lenses than spheric iol implantation. Implanting a foldable aspheric acrylic IOL gave much advantage in visual outcome to pseudophakes by protecting retina from light of shorter wavelength and decrease of chromatic aberration under the photopic circumstances particularly in subjects at hazard of age-related macular degeneration (AMD).
目的:比较超声乳化白内障手术后球形和非球面丙烯酸黄色人工晶状体的视力质量。研究地点:Al-Majeed激光眼科医院。方法:年龄相关性成熟白内障患者60例,年龄40 ~ 65岁。在Al-Majeed激光眼科医院采用非概率方便抽样技术收集数据。所有表现为成熟白内障的患者均纳入本研究,无其他病理和眼底异常。术前、术后视敏度采用标准视敏度测试表测定。为保证准确性,对每位患者进行重复测量。术后1个月行超声乳化术,记录术后视力。采用(描述性)统计和配对样本t检验对球形和非球形丙烯酸黄色人工晶状体进行比较分析。结果:比较了同一位晶状体手术下非球面亲水丙烯酸人工晶状体与球形人工晶状体后房植入术后的视力质量。眼内植入术后的矫正视力较好,达到6/9,较好,提高了6/6。两种类型的人工晶状体中,非球面黄色人工晶状体与球状人工晶状体的记录视力差异有统计学意义(p = 0.15)。球型人工晶状体的平均值、标准差、t值分别为。1867年,18889年,2517年。而非球面亲水丙烯酸人工晶状体的平均值、标准差和t值分别为0.800、0.13493和2.5493。两种类型的镜片在统计数据和视觉质量上有显著差异。结论:非球面亲水黄色人工晶状体术后视力质量的改善优于球形人工晶状体植入术。植入可折叠的非球面丙烯酸人工晶状体对假晶状体的视力有很大的好处,它可以保护视网膜免受波长较短的光的影响,并减少光环境下的色差,特别是在有年龄相关性黄斑变性(AMD)危险的受试者中。
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引用次数: 1
The detection of COAT’s disease at its early stage and management 大衣病的早期发现及治疗
Pub Date : 2021-04-23 DOI: 10.15406/AOVS.2021.11.00402
R. Shah
Coats disease is the potential leading cause of blindness which is an idiopathic disorder characterized by progressive deposition of intraretinal or subretinal exudates and abnormal development of retinal vasculatures known as telangiectasia that leads to exudative retinal detachment. The case shows unilateral involvement of the eye and primarily at an early age of 12 years. The cause of the disease is idiopathic and if associated with other genetic disorders emphasizes the deposition of a genetic component. The underlying histopathological problem is thought due to the abnormal permeability of capillary endothelial cells of the retina. The complications of long-standing disease may progress to total retinal detachment, leukocoria, painful Glaucoma and can be hard to differentiate from retinoblastoma. The diagnostic tools are indirect ophthalmoscopy, fluorescein angiography, CT scan, and MRI. The treatment depends on the closure of abnormal leaking vessels of the retina which is laser therapy and anti-VEGF at its early stage. The advanced stage requires surgical therapy such as scleral buckling, pars plana vitrectomy, and anterior vitrectomy for reattachment of the retina or pre retinal membrane. A careful selection therapy showed a 70% improvement in the clinical course of the disease
Coats病是一种特发性疾病,其特征是视网膜内或视网膜下渗出物的进行性沉积和视网膜血管的异常发育,即毛细血管扩张,导致渗出性视网膜脱离。该病例显示单侧眼部受累,主要发生在12岁早期。该病的病因是特发性的,如果与其他遗传疾病有关,则强调遗传成分的沉积。潜在的组织病理学问题被认为是由于视网膜毛细血管内皮细胞的异常通透性。长期疾病的并发症可能发展为视网膜完全脱离,白斑,疼痛性青光眼,并且很难与视网膜母细胞瘤区分。诊断工具为间接眼镜检查、荧光素血管造影、CT扫描和MRI。治疗依赖于关闭视网膜的异常渗漏血管,这是激光治疗和早期抗vegf。晚期需要手术治疗,如巩膜扣合、玻璃体切割、前玻璃体切割以重新附着视网膜或视网膜前膜。经过精心选择的治疗方法使临床病程改善了70%
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引用次数: 0
To evaluate the retinal nerve fiber layer thickness in different types of glaucoma 评价不同类型青光眼视网膜神经纤维层厚度
Pub Date : 2021-02-25 DOI: 10.15406/AOVS.2021.11.00400
Aqsa Batool, Iqra Nehal, A. Riaz, M. Javed, T. Hussain, Abdul Hameed Talpur, Shua Azam
Objective: Glaucoma is a multifaceted eye disease which is classified as physical damage of retinal ganglion cells which may effect in loss of vision and permanent blindness. While physical damage of glaucoma can be clinically evaluated the optic nerve head and peripapillary retinal nerve fiber layer (RNFL). Our objective is to evaluate the mean RNFL thickness in all types of glaucoma. Methodology: This prospective and cross sectional study was conducted in Glaucoma Clinic of Al Ibrahim Eye Hospital (AIEH), Karachi, for the period from May 2019 to October 2019, after ethical approval from Institutional Research Committee. A total of 64 glaucoma patients were chosen by using non-probability purposive sampling technique. The participant comprised, no known eye disease, no visual impairment, IOP below 22 mmHg, and no obvious retinal disease or defect were included while individuals having a history of ocular diseases or pathology with residual visual impairment, retinal diseases, amblyopia, and history of intraocular surgery or laser therapy were excluded from the study. The collected data were analyzed using Statistical Package for Social Sciences (SPSS) version 20. Results: 64 patients of both genders with mean age of 55.54±15.58 years. The mean intraocular pressure of right eye and left eye was 16.46±8.06 and 16.75±7.82 mmHg, respectively. The mean RNFL thickness in superior, inferior, temporal and nasal quadrant of the right eye was measured 68.23±25.44, 66.79±27.50, 51.75±12.58 and 47.73±18.82 microns, respectively while the mean RNFL thickness in superior, inferior, temporal and nasal quadrant of the left eye was measured 76.01±22.72, 67.42±21.25, 54.37±13.0 and 49.62±11.57 microns, respectively. Conclusion: Our study showed that analysis of retinal nerve fiber layer thickness with optical coherence tomography is the best tool for the diagnosis of glaucoma. It has also been observed in our study that frequency of changes in retinal nerve fiber layer thickness was mostly found in primary open angle glaucoma patients
目的:青光眼是一种以视网膜神经节细胞的物理损伤为特征的多面性眼病,可导致视力丧失和永久性失明。而青光眼的物理损伤可从视神经头和乳头周围视网膜神经纤维层(RNFL)进行临床评价。我们的目的是评估所有类型青光眼的RNFL平均厚度。方法:经机构研究委员会伦理批准,本前瞻性横断面研究于2019年5月至2019年10月在卡拉奇Al Ibrahim眼科医院(AIEH)青光眼诊所进行。采用非概率目的抽样方法,选取64例青光眼患者。参与者包括:无已知眼病、无视力损害、IOP低于22 mmHg、无明显视网膜疾病或缺陷;有眼病病史或病理伴有残余视力损害、视网膜疾病、弱视、眼内手术或激光治疗史者排除在研究之外。收集的数据使用SPSS (Statistical Package for Social Sciences)第20版进行分析。结果:男女64例,平均年龄55.54±15.58岁。右眼、左眼平均眼压分别为16.46±8.06、16.75±7.82 mmHg。右眼上、下、颞、鼻部RNFL平均厚度分别为68.23±25.44、66.79±27.50、51.75±12.58和47.73±18.82 μ m;左眼上、下、颞、鼻部RNFL平均厚度分别为76.01±22.72、67.42±21.25、54.37±13.0和49.62±11.57 μ m。结论:光学相干断层扫描分析视网膜神经纤维层厚度是诊断青光眼的最佳工具。我们的研究也发现,视网膜神经纤维层厚度改变的频率多见于原发性开角型青光眼患者
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引用次数: 0
An atypically distributed fleck case with multiple retinal pigment epithelial detachments 非典型分布的斑点病例伴多发视网膜色素上皮脱离
Pub Date : 2021-02-15 DOI: 10.15406/AOVS.2021.11.00399
S. Cate, Çağlar Bektaş, B. Turgut
A 45-year-old female patient presented with complaints of blurred vision and metamorphopsia with a duration of two months. Visual acuities were 0.1 in the right eye and 1.0 in the left eye. Fundus examination revealed bilateral, subretinal, round and yellow-white flecks with scattered localization in the fovea, macula and peripheral retina. Flecks were mostly concentrated in the macula and midperipheral fundus however were rare in the peripheral fundus. In fluorescein angiography, flecks were stained as well-demarcated hyperfluorescent lesions. In optical coherence tomography, there were hump-shaped lesions which have medium degree internal reflectivity at the level of retinal pigment epithelium along with hyporeflective dome-shaped pigment epithelial detachments. No genetic predisposition was found. As a consequence of these findings, the patient was diagnosed with an atypically distributed fleck case with multiple retinal pigment epithelial detachments
患者女,45岁,主诉视力模糊、变形,病程2个月。右眼视力0.1,左眼视力1.0。眼底检查显示双侧,视网膜下,圆形和黄白色斑点,分散定位于中央凹,黄斑和周围视网膜。斑点主要集中在黄斑和中周眼底,外周眼底少见。在荧光素血管造影中,斑点被染色为界限清晰的高荧光病变。光学相干断层扫描显示,视网膜色素上皮水平有中等程度内反射率的驼峰状病变,并伴有低反射率的圆顶状色素上皮脱离。没有发现遗传易感性。由于这些发现,患者被诊断为非典型分布的斑点病例,多发性视网膜色素上皮脱落
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引用次数: 0
Assessment of spontaneous eye blink rate in online livestream videogame players 在线直播视频游戏玩家自发眨眼率的评估
Pub Date : 2021-01-01 DOI: 10.15406/aovs.2021.11.00401
Joana E. Andoh, B. DeBroff
Introduction: The normal blink rate for humans is between 12 and 15 blinks per minute (bpm). Screen use has been associated with decreased blink rate and increased percentage of incomplete blinks, however, little is known about the effects of videogaming on blink rate. The purpose of this study was to assess the blink rate of online livestream video game players. Methods: A total of 30 livestream video gamers across YouTube, Twitch, and Facebook Gaming were selected for this study. Video gamers were characterized by gender and whether or not they were wearing glasses. Blink rate was observed for 5 minutes and defined as a complete closure of the ocular surface. Descriptive statistics and linear regression were used to determine significance (p<0.05) between variables. All analyses were conducted using RStudio (version 1.3.1056; RStudio, Inc). Results: The study population comprised of 30 video game players (50% men). The mean (standard deviation [SD]) blink rate of the total study population was 14.79 (8.79) bpm. Compared to male gamers, female gamers had a higher mean blink rate, however this was not statistically significant (17.07 vs. 12.51, p=0.16). A total of 3 (10%) video game players wore glasses. The difference in blink rate between video game players wearing and not wearing glasses was not statistically significant (14.07 vs 14.87, p=0.88). Conclusions: The average blink rate of select livestream video game players was observed to be within the range of normal spontaneous blink rates. The observed blink rate between male and female gamers did not differ. More research in controlled environments would help to elucidate the blink rate and patterns of video game players
人类正常的眨眼频率是每分钟12到15次。使用屏幕会降低眨眼频率,增加不完全眨眼的比例,然而,人们对电子游戏对眨眼频率的影响知之甚少。本研究的目的是评估在线直播视频游戏玩家的眨眼率。方法:本研究共选取了YouTube、Twitch和Facebook游戏平台上的30名直播视频玩家。视频游戏玩家的特征是性别和他们是否戴眼镜。观察眨眼频率5分钟,并将其定义为眼表完全闭合。采用描述性统计和线性回归检验变量间的显著性(p<0.05)。所有分析均使用RStudio(版本1.3.1056;RStudio公司)。结果:研究人群包括30名电子游戏玩家(50%为男性)。研究人群眨眼频率的平均值(标准差[SD])为14.79 (8.79)bpm。与男性玩家相比,女性玩家的平均眨眼率更高,但这在统计学上并不显著(17.07 vs. 12.51, p=0.16)。总共有3名(10%)电子游戏玩家戴眼镜。戴眼镜和不戴眼镜的电子游戏玩家眨眼频率的差异没有统计学意义(14.07 vs 14.87, p=0.88)。结论:所选视频游戏直播玩家的平均眨眼频率在正常自发眨眼频率范围内。观察到的男性和女性玩家的眨眼频率没有差异。在受控环境中进行更多的研究将有助于阐明电子游戏玩家的眨眼频率和模式
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引用次数: 1
Relationship between post-op central corneal thickness and steroid-induced ocular hypertension following myopic photorefractive keratectomy 近视屈光性角膜切除术后角膜中央厚度与激素性高眼压的关系
Pub Date : 2020-11-23 DOI: 10.15406/AOVS.2020.10.00398
Hina Manzoor, A. Batool, S. Akram, Iqra Khalil, Ammara Affi
Purpose: Purpose of this study is to determine the relationship between Post-op central corneal thickness and steroid-induced ocular hypertension following myopic photorefractive keratectomy. Methods: This longitudinal analytical study was carried on 50 patients, both gender and age ranging from 20-40 years who had undergone myopic PRK refractive surgery. The data collected from The Department of Ophthalmology in Madina Teaching Hospital Faisalabad in the duration of 11 months from July 2019 to May 2020. IOP measured by Goldmann applanation tonometer. Recorded IOP greater than 21mmHg was considered as Ocular hypertension (OHT). The post-Op follow-up was conducted 1 day, 1 week, 2-3 weeks, and 4-6 weeks. The CCT and IOP was evaluated carefully. Data was noted on Performa. Data was analyzed by using Descriptive and Repeated Measures ANOVA by using the latest version 21 of SPSS. Results: Out of 50 patients’ 46% were males and 54% were females. The mean score of CCT pre & post operatively for right eye and left eye was 529.28±34.74 & 462.56±40.20 and 529.18±37.2, 462.44±42.60 respectively. Statistically significant effect was seen on post-op central corneal thickness and steroid induced ocular hypertension, according to the results of repeated measure ANOVA. Thinner corneas were more susceptible to steroids induced OHT. In various post-op central corneal thickness, it was observed that patients with thinner corneal thickness ranges 413±4.24 to 449.33±48.29 in right eye and 455.8±56.42 to 456.83±50.52 are more affected by topical steroids used. Males were more affected than females due to decreased central corneal thickness. Elderly patients were more susceptible to steroid-induced ocular hypertension post-operatively. Conclusion: Post-op steroid induced ocular hypertension is affecting by central corneal thickness. Male and elderly individual are more susceptible to steroid-induced ocular hypertension following myopic PRK. Post-Op use of topical steroids cause ocular hypertension in thinner corneas
目的:本研究的目的是确定近视屈光性角膜切除术后角膜中央厚度与激素性高眼压的关系。方法:对50例20 ~ 40岁的近视PRK屈光手术患者进行纵向分析研究。数据收集自费萨拉巴德麦地那教学医院眼科,时间为2019年7月至2020年5月,共11个月。用Goldmann眼压计测量眼压。IOP大于21mmHg被认为是高眼压(OHT)。术后随访1天、1周、2-3周、4-6周。仔细评估CCT和IOP。数据记录在performance上。数据分析采用描述性和重复测量方差分析,采用最新版本的SPSS 21。结果:50例患者中男性46%,女性54%。右眼、左眼CCT术前、术后平均评分分别为529.28±34.74、462.56±40.20、529.18±37.2、462.44±42.60。根据重复测量方差分析结果,术后角膜中央厚度和类固醇引起的高眼压有统计学意义。较薄的角膜更容易受到类固醇诱导的OHT的影响。在不同的术后角膜中央厚度中,观察到右眼角膜厚度较薄的患者(413±4.24 ~ 449.33±48.29)和局部使用类固醇激素的患者(455.8±56.42 ~ 456.83±50.52)受影响较大。由于角膜中央厚度减少,男性比女性更容易受到影响。老年患者术后更容易发生激素性高眼压。结论:术后类固醇性高眼压受角膜中央厚度的影响。男性和老年人在近视PRK后更容易发生类固醇性高眼压。术后使用局部类固醇引起薄角膜的高眼压
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引用次数: 1
Managing solitary choroidal tuberculoma in an immunocompetent patient 免疫功能正常患者单发脉络膜结核瘤的处理
Pub Date : 2020-10-20 DOI: 10.15406/AOVS.2020.10.00396
A. Dhami, N. Dhami, R. Malhi, G. Dhami
Aim: We describe a case of young immunocompetent 18-year-old female patient who presented with sudden painless diminution of vision in left eye with vision of 20/100 on Snellen’s chart. Retinal evaluation showed a massive solitary choroidal granuloma. A positive Mantoux test (20X20 mm) was noted. The patient was started on anti-tubercular therapy and oral steroids and showed resolution of the granuloma with subretinal fluid at macula. After 3 months of oral therapy, the persistent subretinal fluid was managed with intravitreal injection of triamcinolone acetonide(2 mg). This case highlights favorable resolution of granuloma with oral therapy and a safer efficacy of triamcinolone acetonide in treating subretinal fluid due to choroidal tuberculoma with good visual outcome. Introduction: Choroidal tuberculoma is a rare ocular form of tuberculosis (TB) and is a diagnostic and a therapeutic challenge, especially when occurring without other manifestations of the disease.1,2 Involvement of the choroid occurs by direct infection or indirect immune‐mediated hypersensitivity and is the commonest clinical manifestation of intraocular TB.3 The presentation varies from a solitary choroidal granuloma (tuberculoma) to multiple choroidal tubercles, a subretinal abscess or choroiditis. We present a case of an immunocompetent patient, who presents with massive choroidal granuloma and responded to oral antitubercular and steroid therapeutic regimen. Visual acuity improved with intravitreal triamcinolone acetonide injection which resulted in resolution of subretinal fluid after 3 months
目的:我们描述了一例18岁的年轻免疫功能正常的女性患者,她的左眼视力突然无痛性下降,在斯伦氏图上视力为20/100。视网膜检查显示一个巨大的孤立脉络膜肉芽肿。Mantoux试验阳性(20x20mm)。患者开始接受抗结核治疗和口服类固醇,黄斑处伴有视网膜下积液的肉芽肿消退。口服治疗3个月后,玻璃体内注射曲安奈德(2mg)治疗持续性视网膜下积液。本病例强调了口服治疗肉芽肿的良好解决方案和曲安奈德治疗脉络膜结核瘤引起的视网膜下积液的更安全的疗效,并具有良好的视觉效果。脉络膜结核瘤是一种罕见的眼部结核(TB),是一种诊断和治疗挑战,特别是在没有其他疾病表现的情况下。1,2脉络膜受累可通过直接感染或间接免疫介导的超敏反应发生,是眼内结核最常见的临床表现。3其表现从单发脉络膜肉芽肿(结核瘤)到多发脉络膜结核、视网膜下脓肿或脉络膜炎不一而足。我们提出一个免疫功能正常的病人,谁提出了大量脉络膜肉芽肿和响应口服抗结核和类固醇治疗方案。玻璃体内注射曲安奈德可改善视力,3个月后视网膜下积液溶解
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引用次数: 0
Colour vision defect among secondary school students in enugu, Nigeria: prevalence, pattern and impact 尼日利亚埃努古中学生的色觉缺陷:患病率、模式和影响
Pub Date : 2020-10-05 DOI: 10.15406/AOVS.2020.10.00394
G. C. Eze, Nkiru Kizor Akaraiwe, A. A. Chime, C. Anajekwu, Ifeoma N. Asimadu, Chima Edoga, I. Ezegwui
Aim: To determine the prevalence, pattern and impact of colour vision defects among public secondary school students in Enugu, Nigeria with a view to guiding the affected students on appropriate career choice. Methods: A descriptive cross-sectional study was carried out among students attending public secondary schools in Enugu-East Local Government Area, Enugu state. A total of 950 students (361 males, 589 females) were selected by multistage sampling. The students were assessed for colour vision using Ishihara 38 plate edition and Farnsworth D-15 colour caps. An interviewer-administered structured questionnaire was used to obtain the socio-demographic data and impact of colour vision on colour-related school tasks and activities of daily living. Data was analysed using statistical package foe social sciences, version 20. Result: The age of the students ranged from 10-20 years with mean age of 14.2 ± 1.9 years. Eleven (1.2%) students were found to have colour vision defect out of whom 9 were boys and 2 were girls, 6 (54.5%) were deutan and 5 (45.5%) were protan. No tritan defect was detected. Greater percentages of the students with colour vision defect had difficulties with colour-related school tasks and daily activities when compared to those with normal colour vision. Conclusion: Colour vision defect may affect students’ performance in colour-related school tasks and activities of daily living. Therefore, early detection of colour vision defect is important so as to guide in the choice of future career
目的:了解尼日利亚埃努古市公立中学学生色觉缺陷的患病率、模式及影响,指导色觉缺陷学生进行正确的职业选择。方法:对埃努古州埃努古-东地方政府区的公立中学学生进行描述性横断面研究。采用多阶段抽样法,共抽取大学生950人,其中男生361人,女生589人。学生们使用石原38版平板电脑和法恩斯沃斯D-15色帽来评估色彩视觉。采用问卷调查的方式获取社会人口统计数据,以及色觉对学校色彩相关任务和日常生活活动的影响。数据分析使用统计软件包社会科学,版本20。结果:学生年龄10 ~ 20岁,平均年龄14.2±1.9岁。发现色觉缺陷11例(1.2%),其中男生9例,女生2例,多变性6例(54.5%),蛋白性5例(45.5%)。没有检测到tritan缺陷。与色觉正常的学生相比,有色觉缺陷的学生在与颜色相关的学校任务和日常活动中遇到困难的比例更高。结论:色觉缺陷会影响学生在与色彩相关的学校任务和日常生活活动中的表现。因此,及早发现色觉缺陷,对指导今后职业选择具有重要意义
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引用次数: 0
School vision screening programmes in reducing uncorrected refractive error among children in Low and Middle-Income countries-LMIC (systematic review) 学校视力筛查规划在减少低收入和中等收入国家儿童未矫正屈光不正中的作用(系统评价)
Pub Date : 2020-08-31 DOI: 10.15406/AOVS.2020.10.00392
A. Opare, L. Abdullahi, D. Minnies, C. Cook, Maylene Shung-King, Grace Mwangi
ackground: The prevalence of uncorrected refractive error among school-age children is on the rise with detrimental effect on academic performance and socio-economic status of those affected. School vision screening programmes appear to be an effective way of identifying children with uncorrected refractive errors so early intervention can be made. Despite the increasing popularity of school vision screening programmes over the past few years, there is a lot of debate on its effectiveness in reducing the proportion of children with uncorrected refractive error in the long term, especially in settings where resources are limited. Some studies argue that school vision screening programmes are effective while other studies have reported otherwise. The purpose of this systematic review was to assess the effectiveness of school vision screening programmes in reducing uncorrected refractive error among children in low and middle income countries using evidence from published studies. Methods and findings: A comprehensive and systematic strategy was used to search various databases including PubMed, Cochrane Central Register of Controlled Trials (CENTRAL) which contains the Cochrane Eyes and vision Trial Register, the Cochrane Library, Medline (1980-2018), CINAHL, Academic Search Premier, Web of Science, the WHO’s Library Information System, Africa-Wide and Scopus. The search was restricted to articles published in English. Randomized control trials, cross-sectional studies, case-control studies and cohort studies were included in this review. Participants included school children with refractive error. Full-text review of search results, data extraction and risk of bias assessment was done by two independent reviewers. The certainty of the evidence was assessed using the GRADE approach and data were pooled using the random-effect model. Thirty studies met the inclusion criteria. This review found moderate certainty evidence indicating that school vision screenings may be effective in reducing uncorrected refractive error among school children by 81% (95% CI: 77%; 84%), 24% (95% CI: 13%; 35%) and 20% (95% CI: 18%; 22%) at two, six, and more than six months respectively after its introduction. Results: Results of this review also suggest that school vision screening may be effective in achieving 54% (95% CI: 25%; 100%), 57% (95% CI: 46%; 70%), 37% (95% CI: 26%; 52%), and 32% (95% CI: 14%; 72%) spectacle-wear compliance among school children at less than three months, at three months, at six months and at more than six months respectively after its introduction (low to moderate certainty evidence). This review further found moderate to high certainty evidence indicating that school vision screening, together with provision of spectacles, may be relatively cost effective, safe and has a positive impact on the academic performance of school children. Conclusion: The findings of this review show that school vision screening, together with provision of specta
背景:在学龄儿童中,未矫正屈光不正的患病率呈上升趋势,对这些儿童的学习成绩和社会经济地位产生不利影响。学校视力筛查项目似乎是识别未矫正屈光不正儿童的有效方法,因此可以进行早期干预。尽管在过去几年中,学校视力筛查项目越来越受欢迎,但从长远来看,它在减少未矫正屈光不正儿童比例方面的有效性仍存在很多争议,特别是在资源有限的情况下。一些研究认为,学校视力筛查项目是有效的,而另一些研究则相反。本系统综述的目的是利用已发表研究的证据,评估学校视力筛查项目在减少低收入和中等收入国家儿童未矫正屈光不正方面的有效性。方法和发现:采用全面和系统的策略搜索各种数据库,包括PubMed、Cochrane中央对照试验登记册(Central)(其中包含Cochrane眼睛和视力试验登记册)、Cochrane图书馆、Medline(1980-2018)、CINAHL、学术搜索Premier、Web of Science、世卫组织图书馆信息系统、Africa-Wide和Scopus。检索仅限于用英文发表的文章。本综述包括随机对照试验、横断面研究、病例对照研究和队列研究。参与者包括有屈光不正的学童。全文检索结果、数据提取和偏倚风险评估由两名独立审稿人完成。使用GRADE方法评估证据的确定性,并使用随机效应模型汇总数据。30项研究符合纳入标准。本综述发现中等确定性的证据表明,学校视力筛查可有效减少81%的学龄儿童未矫正屈光不正(95% CI: 77%;84%), 24% (95% ci: 13%;35%)和20% (95% CI: 18%;(22%),分别在推出后2个月、6个月和6个多月。结果:本综述的结果还表明,学校视力筛查的有效性可能达到54% (95% CI: 25%;100%), 57% (95% ci: 46%;70%), 37% (95% ci: 26%;52%)和32% (95% CI: 14%;72%)学童在戴眼镜后不到三个月、三个月、六个月和六个月以上的时间里都有戴眼镜的依从性(低到中等确定性证据)。本综述进一步发现了中等到高确定性的证据,表明学校视力筛查与眼镜的提供可能相对具有成本效益、安全性,并对学龄儿童的学习成绩产生积极影响。结论:本综述的研究结果表明,学校视力筛查与提供眼镜可能是一种安全、经济的方式,可以减少儿童未矫正屈光不正的比例,对儿童的学习成绩有长期的积极影响。然而,本综述中包括的大多数研究都是在亚洲进行的。强烈建议在世界其他地区(如非洲)开展调查学校视力筛查方案有效性的研究,这些地区的研究很少
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引用次数: 2
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Advances in ophthalmology & visual system
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