Recent developments in microfluidic paper-, cloth-, and thread-based electrochemical devices for analytical chemistry

IF 3.6 3区 化学 Q2 CHEMISTRY, ANALYTICAL Reviews in Analytical Chemistry Pub Date : 2017-07-14 DOI:10.1515/revac-2016-0018
R. S. Malon, L. Heng, E. Córcoles
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引用次数: 26

Abstract

Abstract The attractive structural and mechanical properties of cellulose substrates (paper, cloth, and thread), including passive fluid transport, biocompatibility, durability, and flexibility, have attracted researchers in the past few decades to explore them as alternative microfluidic platforms. The incorporation of electrochemical (EC) sensing broadened their use for applications such as clinical diagnosis, pharmaceutical chemical analyses, food quality, and environmental monitoring. This article provides a review on the microfluidic devices constructed on paper, cloth, and thread substrates. It begins with an overview on paper-based microfluidic devices, followed by an in-depth review on the various applications of EC detection incorporated on paper-based microfluidic devices reported to date. The review on paper-based microfluidic devices attempts to convey a few perspective directions that cloth- and thread-based microfluidic devices may take in its development. Finally, the research efforts on the development and evaluation, as well as current limitations of cloth- and thread-based microfluidic devices are discussed. Microfluidic devices constructed on paper, cloth, and thread substrates are still at an early development stage (prototype) requiring several improvements in terms of fabrication, analytical techniques, and performance to become mature platforms that can be adapted and commercialized as real world products. However, they hold a promising potential as wearable devices.
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用于分析化学的基于纸、布和线的微流体电化学装置的最新进展
纤维素基质(纸、布和线)具有引人注目的结构和机械性能,包括被动流体输送、生物相容性、耐久性和柔韧性,在过去的几十年里吸引了研究人员探索它们作为替代微流体平台。电化学(EC)传感的结合扩大了它们在临床诊断、药物化学分析、食品质量和环境监测等应用中的应用。本文综述了基于纸、布和线的微流控装置的研究进展。首先概述了基于纸的微流控装置,然后深入回顾了迄今为止报告的基于纸的微流控装置上的EC检测的各种应用。本文对纸基微流控器件的研究进展进行了综述,并对布基和线基微流控器件的发展方向进行了展望。最后,讨论了基于布和线的微流控装置的发展和评价,以及目前的局限性。在纸、布和线基板上构建的微流体装置仍处于早期开发阶段(原型),需要在制造、分析技术和性能方面进行几次改进,才能成为成熟的平台,可以作为现实世界的产品进行调整和商业化。然而,它们作为可穿戴设备具有很大的潜力。
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来源期刊
Reviews in Analytical Chemistry
Reviews in Analytical Chemistry 化学-分析化学
CiteScore
7.50
自引率
0.00%
发文量
15
审稿时长
>12 weeks
期刊介绍: Reviews in Analytical Chemistry publishes authoritative reviews by leading experts in the dynamic field of chemical analysis. The subjects can encompass all branches of modern analytical chemistry such as spectroscopy, chromatography, mass spectrometry, electrochemistry and trace analysis and their applications to areas such as environmental control, pharmaceutical industry, automation and other relevant areas. Review articles bring the expert up to date in a concise manner and provide researchers an overview of new techniques and methods.
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