Natural mouthwash of sarang banua leaves (Clerodendrum fragrans Vent Willd) extractas a healthy solution during the covid-19 pandemic

Julianse Lydia Nababan, Titin Evania Manalu, R. Aulia, Anna Lestari, Angga Koswara Malau, M. Simorangkir
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Abstract

The spread of the COVID-19 virus has shaken the world. The application of Clean and Healthy Living Behavior (CHLB) is the best effort to prevent the transmission of the Covid-19 virus. Maintaining oral and dental hygiene can improve health, especially during the COVID-19 pandemic. Sarang Banua (Clerodendrum fragrans Vent Willd) is a local plant of North Sumatra, containing secondary metabolites of alkaloids, steroids, flavonoids, triterpenoids, saponins, tannins, and quinones that have bioactivity such as antibacterial and antioxidant. The preparation of Sarang Banua mouthwash (SABANA) made from the extract of the sarang banua leaves with a concentration of 0.5 grams in 100 ml of preparation (0.5%) has been formulated, evaluated by organoleptic, pH and antibacterial test. The results of organoleptic and pH tests showed that SABANA mouthwash preparations were brown and slightly cloudy, tasted very distinctive, fresh, and eliminated bad breath with a pH of 7 in accordance with quality standards. About 70% of the panelists stated that they really liked the color, aroma, taste and appearance of SABANA mouthwash preparations. The results of antibacterial test against the oral bacteria Streptococcus mutans ATCC (25175) showed that 0.5% and 0.75% of the oral antibacterial mouthwash was found to be effective as oral antibacterial with an average inhibition zone diameter of 16.55 and 16.9 mm. Through the activities of the Student Creativity-Entrepreneurship Program, SABANA mouthwash have been produced and marketed in the local as well as outside the city by online and offline-shop and have the opportunity to develop into a new entrepreneur.
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沙蚕叶(Clerodendrum fragrans Vent wild)提取物的天然漱口水是covid-19大流行期间的健康解决方案
COVID-19病毒的传播震惊了世界。实施清洁健康生活行为(CHLB)是预防新冠病毒传播的最佳措施。保持口腔和牙齿卫生可以改善健康,特别是在COVID-19大流行期间。沙朗是北苏门答腊岛的一种本地植物,含有生物碱、类固醇、黄酮类、三萜、皂苷、单宁、醌等次生代谢产物,具有抗菌、抗氧化等生物活性。以沙蚕叶提取物为原料,以0.5克的浓度配制沙蚕叶漱口水(SABANA),并通过感官、pH值和抗菌试验对其进行了评价。感官和pH值测试结果表明,SABANA漱口水制剂呈棕色,微浑浊,味道非常独特,清新,消除了口臭,pH值为7,符合质量标准。大约70%的小组成员表示,他们非常喜欢SABANA漱口水制剂的颜色、香气、味道和外观。对口腔细菌变形链球菌ATCC(25175)的抑菌试验结果表明,0.5%和0.75%的口腔抗菌漱口水具有口腔抗菌效果,平均抑菌带直径分别为16.55和16.9 mm。通过学生创新创业计划的活动,SABANA漱口水已经通过线上和线下商店在当地和城市以外的地方生产和销售,并有机会发展成为一个新的企业家。
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