Update on Pregnancy Following Breast Cancer Diagnosis and Treatment

M. Perachino, F. Poggio, L. Arecco, E. Blondeaux, S. Spinaci, C. Marrocco, A. Levaggi, M. Lambertini
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Abstract

Abstract Survivorship has become a crucial component in breast cancer care. For women who have not completed their family planning, conceiving at the end of anticancer treatments should not be discouraged but might be challenging. Oncofertility counseling should be offered at the time of diagnosis to all patients, in order to inform them about the potential treatment-induced gonadotoxicity as well as the available strategies for fertility preservation, thus allowing to increase the chances of a future pregnancy. This article reports an updated overview on the current state of the art on pregnancy in women with prior breast cancer diagnosis and treatment, with a main focus on the issues faced by patients with history of hormone receptor–positive disease and BRCA carriers.
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乳腺癌诊断和治疗后妊娠的最新进展
生存率已成为乳腺癌治疗的重要组成部分。对于那些没有完成计划生育的女性来说,在抗癌治疗结束时怀孕不应该被阻止,但可能是具有挑战性的。应在诊断时向所有患者提供肿瘤生育咨询,以便告知他们治疗引起的潜在性腺毒性以及保留生育能力的可用策略,从而增加未来怀孕的机会。本文综述了既往乳腺癌诊断和治疗的妇女妊娠的最新进展,主要关注激素受体阳性病史和BRCA携带者所面临的问题。
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