Multifunctional Magnetic Nanoparticles-A Promising Approach for Cancer Treatment

Maulick Chopra, K. Ganeshlenin, asamy, D. Maity
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引用次数: 1

Abstract

Nanomedicine plays an important role for treating cancer over the conventional treatments or techniques and has marked over in the past few decades. This can be attributed to the studies between cancer and magnetic nanoparticles, established and reported over the past few years. The magnetic nanoparticles exhibit unique characteristics which make them an ideal candidate for the treatment of cancer under the biomedical applications. Magnetic Nanoparticles can be attracted magnetically by an external applied magnetic field and they act as drug carriers to the cancer cells. Magnetic nanoparticles are able to generate the heat in an alternating magnetic field, as the temperature increases (42-45 °C) it can be used to eradicate or inhibit cancer cell activities locally or even to release drugs in a precisely controlled manner and this effect of magnetic nanoparticles is called hyperthermia. Moreover, with the help of magnetic resonance imaging (MRI), magnetic nanoparticles can also be used as a diagnostic tool by using contrast agents. This opinion provides the snapshot on the properties and application of magnetic nanoparticles in the treatment of cancer.
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多功能磁性纳米粒子——一种很有前途的癌症治疗方法
在过去的几十年里,纳米医学在治疗癌症方面发挥着超越传统治疗方法或技术的重要作用。这可以归因于过去几年建立和报道的关于癌症和磁性纳米颗粒之间关系的研究。磁性纳米颗粒表现出独特的特性,使其成为生物医学应用中治疗癌症的理想候选者。磁性纳米颗粒可以被外部外加磁场吸引,充当癌细胞的药物载体。磁性纳米颗粒能够在交变磁场中产生热量,随着温度的升高(42-45°C),它可以用于局部根除或抑制癌细胞活动,甚至以精确控制的方式释放药物,磁性纳米颗粒的这种效果被称为热疗。此外,在磁共振成像(MRI)的帮助下,磁性纳米颗粒还可以通过使用造影剂作为诊断工具。这一观点提供了磁性纳米颗粒在癌症治疗中的特性和应用的快照。
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