Predictive Value of Maternal Anemia in Cases of Fetal Growth Restriction

W. Tawfik, S. Abdelmaksoud, G. Mahmoud
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Abstract

Anemia can be defined as a state of inadequate O2 delivery to tissues due to reduction of the O2 carrying capacity of blood practically, anemia is diagnosed when there is reduction in the hemoglobin concentration or haematocrit level below normal values. Iron deficiency anemia is a major public health problem among women of reproductive age in most of developing countries approximately 50% of pregnant women and 35% of non pregnant women are anemic. These nutritional disorders, has profound negative effects on pregnancy outcome, health of mothers and babies. The objective of this study: Is to evaluate the maternal anemia during pregnancy as a risk factor for fetal growth restriction. The study was done this study conducted on 120 pregnant women. Pregnant women with inclusion criteria: Singleton pregnancy, Gestational age more than 28 week and Hb level less than 10mg/dl. We exclude multiple pregnancy, Gestational age less than 28 week, Hb level more than 10 mg/dl and other medical disorder with pregnancy. The results of this study reveal the following: There was significant difference between group 1, 2, 3, 4 as regard to Hb level, (PCV), (MCV), (MCH), (MCHC), (Ht) and (CBC). The restriction of fatal growth was significant lower in sever anemic patient rather than mild or moderate anemic patient In conclusions: The result of this study shows that there was restriction of fatal growth was significantly high in sever anemic group than mild or moderate group also, incidence of low birth weight and risk of fatal morbidity or mortality was significantly high in sever anemic group than mild or moderate group.
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母体贫血对胎儿生长受限的预测价值
贫血可以定义为由于血液携氧能力降低而导致向组织输送氧气不足的状态。实际上,当血红蛋白浓度或红细胞压积低于正常值时,就可以诊断为贫血。缺铁性贫血是大多数发展中国家育龄妇女的一个主要公共卫生问题,大约50%的孕妇和35%的非孕妇患有贫血。这些营养失调对妊娠结局、母婴健康都有深远的负面影响。本研究的目的是:评估妊娠期间母亲贫血作为胎儿生长受限的危险因素。这项研究是对120名孕妇进行的。纳入标准的孕妇:单胎妊娠,胎龄大于28周,Hb水平小于10mg/dl。我们排除多胎妊娠、胎龄小于28周、Hb水平大于10mg /dl和其他妊娠疾病。本研究结果显示:1、2、3、4组患者Hb水平、(PCV)、(MCV)、(MCH)、(MCHC)、(Ht)、(CBC)差异均有统计学意义。结论:本研究结果显示,重度贫血组的致死性生长限制显著低于轻度和中度贫血组,重度贫血组的致死性生长限制显著高于轻度和中度贫血组,低出生体重发生率和致死性发病或死亡风险显著高于轻度和中度贫血组。
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