Phytochemical, Antimicrobial and Antioxidant studies on the leaf extract of an endemic medicinal plant Canthiumera neilgherrensis(Wight) K.M.Wong (Rubiaceae).

Abstract

Canthiumera neilgherrensis (Wight) K.M. Wong is a rare medicinal plant that is endemic to Southern Western Ghats. Qualitative analysis of phytoconstituents, estimation of total phenol, flavonoids, terpenoids, alkaloids, and steroids, Antioxidant activity is determined by FRAP and DPPH assay, Antibacterial analysis by agar well gel diffusion method wasdone. Phytochemicals are mostly concentrated in chloroform and methanol extracts. The highest inhibition was found in water extract against Pseudomonas aeruginosa and which is a gram-negative bacterium. From the result of the assays, it was clear that chloroform and methanolic extracts show significant inhibitory properties. Higher levels of flavonoids and phenols were the reason behind both the antioxidant and antibacterial activities.