To assess activity-related dyspnea in chronic obstructive pulmonary disease patients

Subah Sahni, Devendra Singh, Tarana Sarwat, Rahul Verma, Jyoti Mishra, Mohan Gupta
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Abstract

BACKGROUND: Chronic obstructive pulmonary disease (COPD) is currently the fourth leading cause of death in the world. COPD is a growing global health concern affecting over 300 million people worldwide and contributing to ~3 million deaths every year. COPD being a respiratory disorder affects the daily routine activities of people and causes immobilization and makes them bedridden due to dyspnea causing activity limitation. This study aimed to assess this activity-related dyspnea in COPD. MATERIALS AND METHODS: This cross-sectional study was conducted among COPD patients. Patients were assessed based on a detailed history, thorough clinical examination, chest X-ray, sputum for Ziehl–Neelsen staining, and electrocardiogram to fulfill the inclusion and exclusion criteria. Furthermore, spirometry, Modified Medical Research Council (mMRC) Dyspnea scale, COPD assessment test (CAT) score, and Borg's scale were used to assess the activity-related dyspnea grading. RESULTS: Among 110 participants, the mean age was 57.51 ± 10.86 years with equal gender distribution. The majority of participants (33.6%) showed mMRC grade II dyspnea and medium range CAT category and obstructive pattern on spirometry (92.7%). Hence, there was a linear correlation between the CAT score and the mMRC dyspnea score. CONCLUSION: Based on our findings, we can conclude that these patients' activities of daily living should be examined, and patients should be directed by a complete multidisciplinary team to offer them better advice to prevent, diagnose, and early treatment of dyspnea.
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评估慢性阻塞性肺疾病患者活动相关性呼吸困难
背景:慢性阻塞性肺疾病(COPD)目前是世界上第四大死亡原因。慢性阻塞性肺病是一个日益严重的全球健康问题,影响全世界3亿多人,每年造成约300万人死亡。慢性阻塞性肺病是一种呼吸系统疾病,影响人们的日常活动,由于呼吸困难导致活动受限,使人们无法活动,卧床不起。本研究旨在评估COPD患者与活动相关的呼吸困难。材料和方法:本横断面研究在COPD患者中进行。根据详细的病史、全面的临床检查、胸部x线片、Ziehl-Neelsen染色痰液和心电图对患者进行评估,以满足纳入和排除标准。此外,采用肺活量测定法、改良医学研究委员会(mMRC)呼吸困难量表、COPD评估测试(CAT)评分和Borg量表评估活动相关呼吸困难分级。结果:110例患者平均年龄57.51±10.86岁,性别分布均匀。大多数参与者(33.6%)显示mMRC II级呼吸困难和中度CAT类别,肺活量测定显示阻塞性(92.7%)。因此,CAT评分与mMRC呼吸困难评分之间存在线性相关。结论:根据我们的研究结果,我们可以得出结论,这些患者的日常生活活动应该被检查,患者应该由一个完整的多学科团队指导,为他们提供更好的建议,以预防、诊断和早期治疗呼吸困难。
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