Determinants of Defaulting Tuberculosis Treatment in Hosanna town health facility, Hadiya Zone, South Ethiopia

Abstract

Background: Treatment non-adherence leads to continuing tuberculosis (TB) transmission, development of drug resistance, resulting in serious risks for patient and for community. Objective: To assess determinant factors of TB defaulting among TB patients in Hosanna town health facility, South Ethiopia. Method: an unmatched case control study was conducted from January 1, 2010 to December 30, 2012. Bivariate and multivariate logistic regression analysis were performed to determine final predictors of defaulting variable at P-value < 0.05 and 95% CI. Result: A total of 128 respondents were included. Among those, 64 of them were controls and 64 were cases. Patients who live in private house and in relative house were 4.12 [AOR (95%CI) = 4.12 (1.1, 15, 4)] and 42.7 [AOR (95%CI) = 42.7(8.5, 213)], times more likely to default as compared to patients who live in their own house respectively ,patients who haven’t experience of stigma were found to decrease odds of defaulting [AOR (95%CI) = 0.1(0.03, 0.44)] and patients who have no awareness of TB treatment period were 22 times more likely to default [AOR (95%CI) = 22.6 (4.3, 118)]. Conclusion: Inadequate knowledge about TB treatment period, housing status, and experience of stigmatization were found to be statistically significant with defaulting TB drug.