Correlation Between Ocular Rigidity With Intraocular Pressure In Patient With Type 2 Diabetes Mellitus

Roland Iqbal, Prima Maya Sari, Ramzi Amin, Fidalia
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Abstract

ABSTRACT Introduction and Objectives: Diabetes mellitus (DM) is known to have a biomechanical effect on tissue. High blood glucose concentrations that lead to increased production of free radical intermediates causes ocular rigidity (OR) changes. This change can effect intraocular pressure (IOP) in patients with type 2 DM. This study to determine correlation between ocular rigidity with IOP in patients with type 2 DM. Methods: A cross-sectional study with a correlation test design of OR with IOP in type 2 DM patients was conducted in RSUP dr. Mohammad Hoesin Palembang from January until June 2018. Eighty eye samples consist of 60 type 2 DM and 20 control group. IOP examination was performed using a Goldmann applanation tonometer and OR measurements using schiotz tonometer with two loads then assessed in Friedenwald differential tables. Result: There was a significant correlation between diabetic retinopathy and OR (p=0,000). There was a significant correlation between OR and IOP in NPDR and PDR group (p=0,000). There was a significant relationship between patient age with OR and IOP (p<0,05). Conclusion: There is a significant correlation between ocular rigidity and IOP in people with type 2 DM.
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2型糖尿病患者眼强直与眼压的相关性研究
摘要简介和目的:糖尿病(DM)已知对组织有生物力学影响。高血糖浓度导致自由基中间体产生增加,引起眼强直(OR)变化。这种变化会影响2型糖尿病患者的眼内压(IOP)。本研究旨在确定2型糖尿病患者眼刚性与IOP之间的相关性。方法:2018年1月至6月,RSUP Mohammad Hoesin Palembang博士在2型糖尿病患者中进行了一项横断研究,并进行了OR与IOP的相关试验设计。2型糖尿病60例,对照组20例。使用Goldmann压平眼压仪进行IOP检查,使用两种负荷的schiotz眼压仪进行OR测量,然后在Friedenwald微分表中进行评估。结果:糖尿病视网膜病变与OR有显著相关性(p= 0000)。NPDR组和PDR组OR与IOP有显著相关性(p= 0000)。患者年龄与IOP有显著相关性(p< 0.05)。结论:2型糖尿病患者眼强直与IOP有显著相关性。
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