Tirzepatide: Revolutionary Drug in Management of “Diabesity”

Vansh Chouhan, Simran Spal, Rakesh Kumar
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Abstract

Tirzepatide, a glucose-dependent insulinotropic polypeptide receptor and glucagon-like peptide-1 receptor agonist has recently been approved by FDA for type 2 diabetes in adults as a single dose weekly. Tirzepatide is in phase 3 development for adults with obesity or overweight with weight-related comorbidity. Tirzepatide is also under evaluation for treatment of non-alcoholic steatohepatitis, heart faialure and obstructive sleep apnea.
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替西肽:治疗“糖尿病”的革命性药物
tizepatide是一种葡萄糖依赖性胰岛素性多肽受体和胰高血糖素样肽-1受体激动剂,最近已被FDA批准用于成人2型糖尿病,每周单剂量。替西帕肽正处于3期研究阶段,用于治疗肥胖或超重伴体重相关合并症的成人。替西帕肽也在评估治疗非酒精性脂肪性肝炎、心力衰竭和阻塞性睡眠呼吸暂停。
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