Synthesis and antimicrobial activity of Cu (III) schiff base complex

S. Chandraleka, S. Basha, G. Chandramohan, A. Panneerselvam, D. Dhanasekaran
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引用次数: 2

Abstract

The study report the synthesis of the Cu(III), with Isonicotinic acid hydrazide and 2-acetylnaphthalene and their characterization using FTIR and Magnetic susceptibility studies. Our studies reveal the presence of different mode of linkages of the ligand with Cu(III), The comparison of the IR spectra of the ligand imply that the ligand is bidentate with the amide group and azomethine –nitrogen as the two coordination sites. The complexes exhibit an identical pattern suggesting them to be isostructural with six coordinated spin free octahedral complexes. The complexes have been screened for their antibacterial and antifungal activity. The results of this study shows that the Cu(III), complex is effective against fungal pathogen than the bacterial pathogens.
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铜(III)席夫碱配合物的合成及其抑菌活性
本文报道了异烟酸肼和2-乙酰萘合成Cu(III),并用FTIR和磁化率对其进行表征。我们的研究表明该配体与Cu(III)存在不同的键模式,红外光谱的比较表明该配体为双齿体,酰胺基团和亚甲基氮为两个配位位点。配合物表现出相同的模式,表明它们与六个配位的无自旋八面体配合物是同构的。对这些配合物进行了抗菌和抗真菌活性的筛选。本研究结果表明,Cu(III),配合物对真菌病原体的杀伤效果优于细菌病原体。
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