Spectral Diffuse Reflectance Imaging Based on Numerical Simulation for Light Transport in Biological Tissues

I. Nishidate, S. Kawauchi, Shunichi Sato, M. Sato, K. Niizeki, Y. Aizu
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Abstract

Diffuse optical spectroscopy provides functional and morphological information of living tissues based on optical absorption and scattering properties. Diffuse reflectance spectroscopy (DRS) can be achieved with simple and low cost equipment, and has been widely applied to in vivo measurements and imaging of biological tissues. In the present article, in vivo evaluation of hemodynamics and changes in tissue morphology by using DRS based on the Monte Carlo simulation for light transport in biological tissues and its application to biomedical imaging are described.
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基于光在生物组织中传输数值模拟的光谱漫反射成像
漫射光谱学基于光学吸收和散射特性提供了活体组织的功能和形态信息。漫反射光谱(DRS)可以用简单和低成本的设备实现,已广泛应用于生物组织的体内测量和成像。本文描述了基于蒙特卡罗模拟光在生物组织中传输的DRS在体内对血流动力学和组织形态学变化的评价及其在生物医学成像中的应用。
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