COVID-19 Rapid Diagnostic test results and their associations with certain factors among the residents of Balochistan.

E. Larik, M. Arif, A. Saeed, M. Baig, Z. Hussain, Ambreen Chaudhary, Z. Baig, Z. Bugti, Jan Inayat, Khair Muhammad, Muhammad Abdullah, Z. Ahmed, Qurat-ul-ain, A. Kakar, Nasir Sheik
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引用次数: 1

Abstract

Background: This paper analyses any possible association of various factors like gender, last COVID-19 PCR test results, BCG Vaccination, Seasonal Flu vaccination, Occupation and confirmed case contact history with COVID-19 RDT results of the participants. COVID-19 will soon become endemic in Pakistan, the government should adopt COVID-19 RDT kits for trace, test and quarantine activities. Methodology: Considering the availability of COVI-19 rapid diagnostic kits, 596 individuals all previously COVID-19 PCR tested were made part of this cross sectional study. Simple random sampling was used for the selection of study participants. The whole study was conducted during September and October 2020. Results: The major findings of this study is clearly showing that the Positive Likely hood ratio of the COVID-19 RDT Kits (LR+) is well above 1; similarly the Negative Likely hood ratio is approaching 0.On the other hand the Sensitivity and Specificity 80% and 74% respectively .Similarly study found statistically significant association was between RDT out comes and Last PCR Test status, Occupation and Contact with COVID-19 positive individuals. While other variables like Gender, BCG Vaccination and history of seasonal flu vaccinations were found to have no significant associations with COVID-19 RDT Kit out comes. Conclusion: Being the first study of its kind in Pakistan the major findings of this study are almost in line with the set hypothesis and objectives of this study and based on study findings it will be of high value to use COVID-19 RDT kits during mass screening especially during Test, Trace and Quarantine activities.
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俾路支省居民新冠肺炎快速诊断检测结果及其与某些因素的关系
背景:本文分析性别、最近一次COVID-19 PCR检测结果、卡介苗接种、季节性流感疫苗接种、职业和确诊病例接触史等各种因素与参与者COVID-19 RDT结果的可能关联。COVID-19将很快在巴基斯坦流行,政府应采用COVID-19 RDT试剂盒进行追踪、检测和隔离活动。方法:考虑到COVID-19快速诊断试剂盒的可用性,596名先前进行过COVID-19 PCR检测的个体被纳入本横断面研究。研究对象的选择采用简单随机抽样。整个研究在2020年9月至10月进行。结果:本研究的主要发现清楚地表明,COVID-19 RDT试剂盒(LR+)的阳性可能比远高于1;同样,负可能性比接近于0。另一方面,灵敏度和特异性分别为80%和74%。同样的研究发现,RDT结果与最后一次PCR检测状态、职业和与COVID-19阳性个体的接触有统计学意义。而性别、卡介苗接种和季节性流感疫苗接种史等其他变量被发现与COVID-19没有显著关联。结论:作为巴基斯坦同类研究的第一项研究,本研究的主要发现几乎符合本研究设定的假设和目标,根据研究结果,在大规模筛查期间使用COVID-19 RDT试剂盒,特别是在检测、追踪和检疫活动期间,将具有很高的价值。
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