In-vitro antioxidant activity of different fraction of roots of Cassia auriculata Linn.

Drug Invention Today Pub Date : 2013-06-01 DOI:10.1016/j.dit.2013.05.006

Supriya Deshpande, Shailesh M. Kewatkar, Vivek V. Paithankar

{"title":"In-vitro antioxidant activity of different fraction of roots of Cassia auriculata Linn.","authors":"Supriya Deshpande, Shailesh M. Kewatkar, Vivek V. Paithankar","doi":"10.1016/j.dit.2013.05.006","DOIUrl":null,"url":null,"abstract":"<div>The aim of this work was to estimate the total phenolic and flavonoid content, and to evaluate in-vitro antioxidant activity of flavonoids rich extract of Cassia auriculata Linn. (CAF) saponins rich extract of C. auriculata Linn. (CAS) which belongs to the family Caesalpiniaceae. Total phenolic content in CAF was found to be 67.32 μg/mg of extract calculated as gallic acid equivalent (r2 = 0.976) and total flavonoids compound was found to be 31 μg/mg of extract calculated as rutin equivalent (r2 = 0.985). The extract was screened for its potential antioxidant activities using tests such as DPPH free radical scavenging activity, reducing power activity, and hydrogen peroxide-scavenging activity. The in-vitro antioxidant assay showed that both CAF as well as CAS posses antioxidant activity. So C. auriculata Linn. could be useful for preparation of neutraceuticals as potent antioxidants, to treat various human diseases and its complications.</div>","PeriodicalId":11284,"journal":{"name":"Drug Invention Today","volume":"5 2","pages":"Pages 164-168"},"PeriodicalIF":0.0000,"publicationDate":"2013-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.dit.2013.05.006","citationCount":"12","resultStr":null,"platform":"Semanticscholar","paperid":null,"PeriodicalName":"Drug Invention Today","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S097576191300032X","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 12

Abstract

The aim of this work was to estimate the total phenolic and flavonoid content, and to evaluate in-vitro antioxidant activity of flavonoids rich extract of Cassia auriculata Linn. (CAF) saponins rich extract of C. auriculata Linn. (CAS) which belongs to the family Caesalpiniaceae. Total phenolic content in CAF was found to be 67.32 μg/mg of extract calculated as gallic acid equivalent (r² = 0.976) and total flavonoids compound was found to be 31 μg/mg of extract calculated as rutin equivalent (r² = 0.985). The extract was screened for its potential antioxidant activities using tests such as DPPH free radical scavenging activity, reducing power activity, and hydrogen peroxide-scavenging activity. The in-vitro antioxidant assay showed that both CAF as well as CAS posses antioxidant activity. So C. auriculata Linn. could be useful for preparation of neutraceuticals as potent antioxidants, to treat various human diseases and its complications.

Abstract Image

查看原文

微信好友朋友圈 QQ好友复制链接

本刊更多论文

黑木香根不同部位体外抗氧化活性的研究。

研究了木耳决明子提取物的总酚和类黄酮含量，并对其体外抗氧化活性进行了评价。(CAF)黑木耳总皂苷提取物。(CAS)，属于凯撒科。以没食子酸当量计算的CAF总酚含量为67.32 μg/mg (r2 = 0.976)，以芦丁当量计算的总黄酮含量为31 μg/mg (r2 = 0.985)。通过DPPH自由基清除活性、还原力活性和过氧化氢清除活性等测试来筛选提取物的潜在抗氧化活性。体外抗氧化实验表明，CAF和CAS均具有抗氧化活性。所以金耳草。可用于制备作为强效抗氧化剂的中性保健品，用于治疗各种人类疾病及其并发症。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

求助全文

约1分钟内获得全文去求助

来源期刊

Drug Invention Today

自引率

0.00%

发文量